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Skip search results from other journals and go to results- 178 JMIR Cancer
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We included participants aged ≥20 years with a self-reported history of cancer in this study. They were asked, “Have you ever been told by a doctor or other health professional that you had cancer or a malignancy of any kind?” A positive response to this question indicated a cancer diagnosis. We excluded participants if they (1) were diagnosed solely with nonmelanoma skin cancer and had no other cancer types or (2) did not report the age at which they were diagnosed with cancer.
JMIR Cancer 2025;11:e71937
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Risk prediction models for cancer could improve early detection rates. These models combine patient data, such as patient demographics, medical history, or cancer symptoms, to identify patients with an increased risk of undiagnosed cancer.
Blood tests commonly performed in clinical practice, including full blood count (FBC) and liver function tests, are often included in cancer risk prediction models, as they have an important role in risk-stratifying symptomatic patients for cancer investigation [10,11].
JMIR Cancer 2025;11:e70275
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Since 2018, Dutch pediatric cancer care has been centralized at the Princess Máxima Center, optimizing treatment outcomes and reducing toxicity [22]. Building on this model, the national Cancer in Pregnancy (CIP) offspring outpatient clinic was allowed to be hosted in this center to monitor all Dutch children prenatally exposed to maternal cancer and its treatment.
JMIR Res Protoc 2025;14:e71612
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Cancer remains the second leading cause of death globally, with continually rising incidence rates each year [4]. Advances in cancer treatment and early detection have contributed to prolonged survival, even for patients in advanced stages. Nevertheless, extended survival often results in protracted suffering, posing significant physical, emotional, social, and spiritual challenges for both patients and their families, especially during the end-of-life phase [5].
JMIR Cancer 2025;11:e71596
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Case 2: Josh
A 56-year-old Black man named Josh previously had colorectal cancer. His sister participated in In Our DNA SC based on a recommendation from her doctor. Josh’s sister convinced him that it would be beneficial for him to participate. He reluctantly agreed to participate but did not see much of a point since he had already been treated for colorectal cancer. Josh received results showing that he was positive for the MLH1 gene, which means he has Lynch syndrome.
JMIR Cancer 2025;11:e65848
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Consequently, the development and widespread adoption of effective screening strategies have become paramount in the fight against cancer.
Among these strategies, genetic testing has emerged as a pivotal tool in cancer prevention and early detection [3]. By analyzing an individual’s DNA, genetic testing can identify mutations that may predispose individuals to various forms of cancer [4].
JMIR Cancer 2025;11:e67650
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The incidence and mortality rates of cancer are rapidly increasing globally. According to the International Agency for Research on Cancer, there were 19.29 million new cancer cases and 9.96 million cancer deaths worldwide in 2020, and the rise in cancer incidence and mortality rates has resulted in a significant disease burden on people [1]. The diagnosis and long-term treatment of cancer not only cause adversity for patients but also impose psychological stress and burdens on caregivers [2].
JMIR Cancer 2025;11:e67131
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However, in the past 3 years, an average of only 216 pediatric patients were diagnosed with cancer annually [5]. This suggests that the remaining 75%‐80% of patients remain undiagnosed and likely do not survive (Figure 1). One example is pediatric leukemia, the most common type of pediatric cancer in this region. Although this malignancy should represent 300‐480 cases (ie, 30%‐40% of all pediatric cancer diagnosis), only 40 cases per year have been seen over the last several years [5].
JMIR Form Res 2025;9:e59776
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Both versions of the Pan CAN Patient Registry were designed to assist the pancreatic cancer community in understanding the “Right Track” for any patient with pancreatic cancer: right team, right tests, right treatment, and the opportunity to share their data [6].
J Particip Med 2025;17:e65046
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Breast cancer is more commonly diagnosed in older populations, particularly among women aged 65 years and older in wealthier countries. In the United States, the average age of breast cancer diagnosis is 62 years, and in 2020, women aged 70 years and older accounted for 30% of all new cases of the disease [1,2]. In the European Union, women older than 65 years made up about 44% of all breast cancer cases [3].
JMIR Cancer 2025;11:e64000
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