Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective Pilot Study

Itske Fraterman   ¹ , MSc ;   Lucia Sacchi   ² , PhD ;   Henk Mallo   ³ , MSc ;   Valentina Tibollo   ⁴ , MSc ;   Savannah Lucia Catherina Glaser   ⁵ , MSc ;   Stephanie Medlock   ^{5, 6} , PhD ;   Ronald Cornet   ^{5, 6} , PhD ;   Matteo Gabetta   ² , PhD ;   Vitali Hisko   ⁷ , BA ;   Vadzim Khadakou   ⁷ , BA ;   Ella Barkan   ⁸ , MA ;   Laura Del Campo   ⁹ , PhD ;   David Glasspool   ¹⁰ , PhD ;   Alexandra Kogan   ¹¹ , MSc ;   Giordano Lanzola   ² , PhD ;   Roy Leizer   ¹¹ , MSc ;   Manuel Ottaviano   ¹² , PhD ;   Mor Peleg   ¹¹ , PhD ;   Konrad Śniatała   ¹³ , MSc ;   Aneta Lisowska   ¹³ , PhD ;   Szymon Wilk   ¹³ , PhD ;   Enea Parimbelli   ² , PhD ;   Silvana Quaglini   ² , PhD ;   Mimma Rizzo   ¹⁴ , MD ;   Laura Deborah Locati   ^{15, 16} , MD ;   Annelies Boekhout   ¹ , PhD ;   Lonneke V van de Poll-Franse   ^{1, 17} , PhD ;   Sofie Wilgenhof   ³ , MD, PhD

¹ Department of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

² Department of Electric, Computer and Biomedical Engineering, University of Pavia, Pavia, Italy

³ Department of Medical Oncology, Antoni van Leeuwenhoek, Amsterdam, The Netherlands

⁴ Laboratory of Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri SpA SB IRCCS, Pavia, Italy

⁵ Medical Informatics, Amsterdam UMC - University of Amsterdam, Amsterdam, The Netherlands

⁶ Methodology and Digital Health, Amsterdam Public Health, Amsterdam, The Netherlands

⁷ BITSENS JSC, Vilnius, Lithuania

⁸ Department of Artificial Intelligence for Accelerated Healthcare and Life Sciences Discovery, IBM Research, University of Haifa, Haifa, Israel

⁹ Associazione Italiana Malati di Cancro, Rome, Italy

¹⁰ Deontics Ltd, London, United Kingdom

¹¹ Department of Information Systems, University of Haifa, Haifa, Israel

¹² Life Supporting Technologies, Universidad Politécnica de Madrid, Madrid, Spain

¹³ Institute of Computing Science, Poznan University of Technology, Poznan, Poland

¹⁴ Division of Medical Oncology, Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Bari, Italy

¹⁵ Department of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy

¹⁶ Medical Oncology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy

¹⁷ Department of Medical and Clinical Psychology, Center of Research on Psychological and Somatic Disorders (CoRPS), Tilburg University, Tilburg, The Netherlands