Tools, Programs and Algorithms

Deep Learning–Based Precision Cropping of Eye Regions in Strabismus Photographs: Algorithm Development and Validation Study for Workflow Optimization

Dawen Wu, Yanfei Li, Zeyi Yang, Teng Yin, Xiaohang Chen, Jingyu Liu, Wenyi Shang, Bin Xie, Guoyuan Yang, Haixian Zhang, Longqian Liu

J Med Internet Res 2025 (Jul 17); 27:e74402

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Identifying People Living With or Those at Risk for HIV in a Nationally Sampled Electronic Health Record Repository Called the National Clinical Cohort Collaborative: Computational Phenotyping Study

Eric Hurwitz, Cara D Varley, A Jerrod Anzolone, Vithal Madhira, Amy L Olex, Jing Sun, Dimple Vaidya, Nada Fadul, Jessica Y Islam, Lesley E Jackson, Kenneth J Wilkins, Zachary Butzin-Dozier, Dongmei Li, Sandra E Safo, Julie A McMurry, Pooja Maheria, Tommy Williams, Shukri A Hassan, Melissa A Haendel, Rena C Patel, The National Clinical Cohort Collaborative (N3C) Consortium

JMIR Med Inform 2025 (Jul 11); 13:e68143

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Discovery of Novel Inhibitors of HMG-CoA Reductase Using Bioactive Compounds Isolated From Cochlospermum Species Through Computational Methods: Virtual Screening and Algorithm Validation Study

Toba Isaac Olatoye

JMIRx Bio 2025 (Jul 10); 3:e71675

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Leveraging AI to Drive Timely Improvements in Patient Experience Feedback: Algorithm Validation

Mustafa Khanbhai, Catalina Carenzo, Sarindi Aryasinghe, David Manton, Erik Mayer

JMIR Med Inform 2025 (Jul 10); 13:e60900

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Development and Validation of a Rule-Based Natural Language Processing Algorithm to Identify Falls in Inpatient Records of Older Adults: Retrospective Analysis

Xing Xing Qian, Pui Hing Chau, Daniel Y T Fong, Mandy Ho, Jean Woo

JMIR Aging 2025 (Jul 08); 8:e65195

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External Validation of an Upgraded AI Model for Screening Ileocolic Intussusception Using Pediatric Abdominal Radiographs: Multicenter Retrospective Study

Jeong Hoon Lee, Pyeong Hwa Kim, Nak-Hoon Son, Kyunghwa Han, Yeseul Kang, Sejin Jeong, Eun-Kyung Kim, Haesung Yoon, Sergios Gatidis, Shreyas Vasanawala, Hee Mang Yoon, Hyun Joo Shin

J Med Internet Res 2025 (Jul 07); 27:e72097

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Scalable Precision Psychiatry With an Objective Measure of Psychological Stress: Prospective Real-World Study

Helena Wang, Norman Farb, Bechara Saab

J Med Internet Res 2025 (Jul 07); 27:e56086

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Optimizing Vital Signs in Patients With Traumatic Brain Injury: Reinforcement Learning Algorithm Development and Validation

Hongwei Zhang, Mengyuan Diao, Sheng Zhang, Peifeng Ni, Weidong Zhang, Chenxi Wu, Ying Zhu, Wei Hu

J Med Internet Res 2025 (Jul 03); 27:e63847

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Extracting Knowledge From Scientific Texts on Patient-Derived Cancer Models Using Large Language Models: Algorithm Development and Validation Study

Jiarui Yao, Zinaida Perova, Tushar Mandloi, Elizabeth Lewis, Helen Parkinson, Guergana Savova

JMIR Bioinform Biotech 2025 (Jun 30); 6:e70706

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Causal AI Recommendation System for Digital Mental Health: Bayesian Decision-Theoretic Analysis

Mathew Varidel, Victor An, Ian B Hickie, Sally Cripps, Roman Marchant, Jan Scott, Jacob J Crouse, Adam Poulsen, Bridianne O'Dea, Sarah McKenna, Frank Iorfino

J Med Internet Res 2025 (Jun 19); 27:e71305

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Development of Machine Learning–Based Risk Prediction Models to Predict Rapid Weight Gain in Infants: Analysis of Seven Cohorts

Miaobing Zheng, Yuxin Zhang, Rachel A Laws, Peter Vuillermin, Jodie Dodd, Li Ming Wen, Louise A Baur, Rachael Taylor, Rebecca Byrne, Anne-Louise Ponsonby, Kylie D Hesketh

JMIR Public Health Surveill 2025 (Jun 18); 11:e69220

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A Deep Learning Model for Identifying the Risk of Mesenteric Malperfusion in Acute Aortic Dissection Using Initial Diagnostic Data: Algorithm Development and Validation

Zhechuan Jin, Jiale Dong, Chengxiang Li, Yi Jiang, Jian Yang, Lei Xu, Ping Li, Zhun Xie, Yulin Li, Dongjin Wang, Zhili Ji

J Med Internet Res 2025 (Jun 10); 27:e72649

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Evaluation of Diagnostic Recommendations Embedded in Medication Alerts: Prospective Single-Arm Interventional Study

Yu-Chen Liu, Guan-Ling Lin, Jeremiah Scholl, Yi-Chun Hung, Yu-Jing Lin, Yu-Chuan Li, Hsuan-Chia Yang

J Med Internet Res 2025 (May 27); 27:e70731

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A Robust Cross-Platform Solution With the Sense2Quit System to Enhance Smoking Gesture Recognition: Model Development and Validation Study

Anarghya Das, Juntao Feng, Maeve Brin, Patricia Cioe, Rebecca Schnall, Ming-Chun Huang, Wenyao Xu

J Med Internet Res 2025 (May 20); 27:e67186

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Extracting Multifaceted Characteristics of Patients With Chronic Disease Comorbidity: Framework Development Using Large Language Models

Junyan Zhang, Junchen Zhou, Liqin Zhou, Zhichao Ba

JMIR Med Inform 2025 (May 15); 13:e70096

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Development of a Risk Score to Aid With the Diagnosis of Infections After Spinal Cord Injury: Protocol for a Retrospective Cohort Study

Felicia Skelton, Larissa Grigoryan, Joann Pan, Ashley Collazo, Barbara Trautner

JMIR Res Protoc 2025 (May 08); 14:e52610

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Enhancing Cardiopulmonary Resuscitation Quality Using a Smartwatch: Neural Network Approach for Algorithm Development and Validation

Gaurav Rao, David W Savage, Gabrielle Erickson, Nathan Kyryluk, Pawan Lingras, Vijay Mago

JMIR Mhealth Uhealth 2025 (May 05); 13:e57469

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Developing a Scalable Annotation Method for Large Datasets That Enhances Alarms With Actionability Data to Increase Informativeness: Mixed Methods Approach

Sophie Anne Inès Klopfenstein, Anne Rike Flint, Patrick Heeren, Mona Prendke, Amin Chaoui, Thomas Ocker, Jonas Chromik, Bert Arnrich, Felix Balzer, Akira-Sebastian Poncette

J Med Internet Res 2025 (May 05); 27:e65961

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Using Segment Anything Model 2 for Zero-Shot 3D Segmentation of Abdominal Organs in Computed Tomography Scans to Adapt Video Tracking Capabilities for 3D Medical Imaging: Algorithm Development and Validation

Yosuke Yamagishi, Shouhei Hanaoka, Tomohiro Kikuchi, Takahiro Nakao, Yuta Nakamura, Yukihiro Nomura, Soichiro Miki, Takeharu Yoshikawa, Osamu Abe

JMIR AI 2025 (Apr 29); 4:e72109

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Uncovering Social States in Healthy and Clinical Populations Using Digital Phenotyping and Hidden Markov Models: Observational Study

Imogen E Leaning, Andrea Costanzo, Raj Jagesar, Lianne M Reus, Pieter Jelle Visser, Martien J H Kas, Christian F Beckmann, Henricus G Ruhé, Andre F Marquand

J Med Internet Res 2025 (Apr 28); 27:e64007

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