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This paper is in the following e-collection/theme issue:

Viewpoints on Innovations in Cancer Care and Research (21) Clinical Communication, Electronic Consultation and Telehealth (826) Innovations and Technology for Cancer Prevention and Screening (220) Precision Medicine and Genetics (87) Screening and Early Diagnosis in Pediatrics (45) Chatbots and Conversational Agents (808) Innovations in Cancer Diagnostic and Decision Support (123) Cancer genomic data analysis (13) Generative Language Models Including ChatGPT (883)

Published on in Vol 11 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/65848, first published .
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Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: Prompt Engineering Project

Authors of this article:

Emma Coen1 Author Orcid Image ;   Guilherme Del Fiol2 Author Orcid Image ;   Kimberly A Kaphingst3 Author Orcid Image ;   Emerson Borsato2 Author Orcid Image ;   Jackilen Shannon4 Author Orcid Image ;   Hadley Smith5 Author Orcid Image ;   Aaron Masino1 Author Orcid Image ;   Caitlin G Allen6, 7 Author Orcid Image
Article Authors Cited by (7) Tweetations (2) Metrics

Journals

  1. Moultrie R, Andrews S, Williams K, Kutsa O, Hudnell T, Brailsford J, Aguilar S, Savage S, Biesecker B, Hunter J. Primary care patient and clinician attitudes about population genomic screening, informed decision‐making needs, and the potential for Chatbot technology. Journal of Genetic Counseling 2025;34(4) View
  2. Lin S, Zhou C, Chen H, Zhou X, Yang H, Sun L, Zhang L, Zhang Y. Advances in Hereditary Colorectal Cancer: How Precision Medicine Is Changing the Game. Cancers 2025;17(21):3461 View
  3. Haghighat R, Levi S, Frey M. Artificial Intelligence for Genetic Cancer Risk Assessment in Gynecologic Oncology. Clinical Obstetrics & Gynecology 2026 View
  4. Del Fiol G, Borsato E, Bradshaw R, Bian J, Woodbury A, Gauchel C, Eilbeck K, Maxwell W, Ellis K, Madeo A, Schlechter C, Kukhareva P, Allen C, Kean M, Elkin E, Sharaf R, Ahsan M, Frey M, Davis-Rivera L, Kohlmann W, Wetter D, Kaphingst K, Kawamoto K. GARDE-Chat: a scalable, open-source platform for building and deploying health chatbots. Journal of the American Medical Informatics Association 2026;33(3):593 View
  5. Keels J, Babicheva V, McDonald I, Witt J, Dwyer A. Optimizing Risk Communication for Lynch Syndrome: Results of a Randomized Controlled Trial of Visual Arrays for Genetic Testing. Cancers 2026;18(9):1369 View
  6. Hui V, Tian L, Feng X, Yuan X, Yorke J, Lee Y. Leveraging AI chatbots in supporting breast and ovarian cancer patients: A scoping review. DIGITAL HEALTH 2026;12 View

Conference Proceedings

  1. Putra P, Nurfadhilah E, Pebiana S, Prakasa E. 2025 International Conference on Computer, Control, Informatics and its Applications (IC3INA). Towards a Safe and Trustworthy LLM-RAG Chatbot for Hemodialysis Patient Education: Design, Implementation, and Preliminary Evaluation View