Cancer and Clinical Trials

Clinical Efficacy and Safety Assessment of Specific-Mode Electroacupuncture Stimulation Combined With Paclitaxel for Recurrent Malignant Gliomas: Study Protocol for a Single-Arm Trial

Zhaoxing Jia, Tianxiang Jiang, Yiqing Zhang, Qianyue Chen, Zhong Di, Qi Yuan, Kecheng Qian, Lin Gan, Congcong Ma, Xianming Lin

JMIR Res Protoc 2026 (Jan 29); 15:e84593

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A Telehealth-Based Behavioral Intervention for Cancer-Related Cognitive Decline in Older Adults Undergoing Systemic Therapy for Breast Cancer: Development and Usability Testing

J MacLaren Kelly, Lucia Berkhof, Oscar Y Franco-Rocha, Lewis Mustian, Valerie Targia, Jessica Bauer, Jessica Mortimer, Grace DiGiovanni, Daniel Millstein, Kassandra Scioli, Heidi DAurizio, Lauren DeCaporale-Ryan, Supriya Mohile, Michelle Janelsins, Robert J Ferguson, Alissa Huston, Allison Magnuson

JMIR Form Res 2026 (Jan 28); 10:e85140

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Large Language Models for Supporting Clear Writing and Detecting Spin in Randomized Controlled Trials in Oncology: Comparative Analysis of GPT Models and Prompts

Carole Koechli, Fabio Dennstädt, Christina Schröder, Daniel M Aebersold, Robert Förster, Daniel R Zwahlen, Paul Windisch

JMIR Cancer 2026 (Jan 21); 12:e78221

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Efficacy of Telehealth-Based Coaching to Improve Physical Activity and Overall Experience for Cancer Survivors: Secondary, Mixed Methods Analysis of a Randomized Controlled Trial

Saif Khairat, Erin E Kent, John Geracitano, Kaushalya Mendis, Zhaoqiang Zhou, Carly Bailey, William A Wood

JMIR Cancer 2026 (Jan 15); 12:e78968

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Quality of Life and Metabolomics Analysis in Response to Meal Kit Intervention During Perioperative Chemotherapy in Patients with Early-Stage Breast Cancer: Protocol for a Single-Center Phase Ⅱ Randomized Crossover Trial

Atsushi Fushimi, Eriko Taguchi, Makiko Kamio, Takashi Kazama, Azusa Fuke, Hiroko Nogi

JMIR Res Protoc 2025 (Dec 04); 14:e72715

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Knowledge of Clinical Trials Among US Cancer Survivors: Cross-Sectional Study of HINTS-SEER Data

Aisha Tene Langford, Katrina Renee Ellis, Nancy Buderer, Navreet Singh

JMIR Cancer 2025 (Nov 19); 11:e76187

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Effect of Obesity on Perioperative Outcomes Following Lung Cancer Surgery: Protocol for a Meta-Analysis and Systematic Review

Qiuxiang Wang, Zhishu Li, Xihuan Wang, Bin Li, Chunfeng Wang, Yongguo Xiang

JMIR Res Protoc 2025 (Nov 12); 14:e76315

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Efficacy of Preventive Pressurized Intraperitoneal Aerosol Chemotherapy in Patients With Locally Advanced Gastric Cancer: Protocol for a Prospective Controlled Trial

Altay Kerimkulov, Talgat Uskenbayev, Tomiris Sarina, Meiram Mamlin, Sanzhar Shalekenov, Gulfairus Yessenbayeva, Temirlan Kainazarov, Zhandos Burkitbayev, Baiduisen Ussipbekov, Dina Kovalchuk, Akhror Rakhmankulov, Aidana Rakhmankulova, Abduzhappar Gaipov

JMIR Res Protoc 2025 (Nov 11); 14:e78053

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Efficacy of Fuzheng Quxie Formula Against Postoperative Metastasis of Lung Cancer in Stage IIA-IIIA With Negative Driver Genes: Protocol for a Multicenter, Double-Blind, Randomized Controlled Trial

Fan Xu, Yun Yang, Yinbin Luo, Bin Luo, Jialiang Yao, Yiyang Zhou, Minghua Li, Jianchun Wu, Wenfei Shi, Lei Jiang, Qian Huang, Wentao Fang, Zhihong Fang, Yan Li, Jianhui Tian

JMIR Res Protoc 2025 (Oct 24); 14:e66342

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Translation and Cultural Adaptation of the Measure Yourself Concerns and Wellbeing (MYCaW) Questionnaire Into German: Protocol for the iSWOP Study

Anja Thronicke, Lisa Schille, Katja Adie, Christian Junghanss, Shiao Li Oei, Sophia Johnson, Juliane Roos, Friedemann Schad

JMIR Res Protoc 2025 (Oct 23); 14:e74288

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Frailty Trajectories and Influencing Factors in Patients With Non-Hodgkin Lymphoma During Chemotherapy: Protocol for a Longitudinal Mixed Methods Study

Ruofei Du, Ying Zhang, Huimin Yang, Yating Du, Jin Li, Bingyan Zhang

JMIR Res Protoc 2025 (Oct 03); 14:e76628

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Exploring Barriers and Facilitators to Engagement of an Online Acceptance and Commitment Therapy Intervention for Cancer Survivors With Chronic Painful Chemotherapy-Induced Peripheral Neuropathy: Qualitative Interview Study

Daniëlle van de Graaf, Marije van der Lee, Tom Smeets, Hester Trompetter, Floortje Mols

JMIR Cancer 2025 (Sep 26); 11:e64983

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Small Extracellular Vesicles as Biomarkers in Sarcoma Follow-Up: Protocol for a Prospective, Multicentric Pilot Study

Valentin Vautrot, Alice Hervieu, Aurélie Bertaut, Céline Charon-Barra, Isen Naiken, Sylvain Causseret, Loic Chaigneau, Isabelle Desmoulins, Emilie Rederstoff, Nicolas Isambert, Jessica Gobbo

JMIR Res Protoc 2025 (Sep 09); 14:e63718

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Effect of Immersive Virtual Reality on Chemotherapy-Related Side Effects in Patients Receiving Paclitaxel-Carboplatin With or Without Bevacizumab: 2-Arm Randomized Controlled Trial

Kazuyuki Niki, Satoshi Nakagawa, Misaki Arai, Ayaka Morimoto, Yutaka Ueda

J Med Internet Res 2025 (Aug 14); 27:e65924

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Examining Potential Implicit Bias in Oncologist-Patient Communication (CONNECT): Protocol for an Observational 2-Site Study

Veronica C K Duck, Marsha L Augustin, Jose A Morillo, Aviel N Alkon, Robert M Thomas, Brianna N Richardson, Lihua Li, Kathryn I Pollak, Cardinale B Smith

JMIR Res Protoc 2025 (Aug 14); 14:e66086

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A Web-Based Training Intervention for Primary Care Providers on Preparing Patients for Cancer Treatment Decisions and Conversations About Clinical Trials: Evaluation of a Pilot Study Using Mixed Methods and Follow-Up

Naomi D Parker, Margo Michaels, Carla L Fisher, Alyssa Crowe, Elisa S Weiss, Maria Sae-Hau, Jason Arnold, Andrea Cassells, Domenic Durante, Ji-Hyun Lee, Raymond Mailhot Vega, Ana Natale-Pereira, Taylor S Vasquez, Zhongyue Zhang, Carma L Bylund

JMIR Med Educ 2025 (Jul 17); 11:e66892

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Comparison of Electronic Surveillance With Routine Monitoring for Patients With Lymphoma at High Risk of Relapse: Prospective Randomized Controlled Phase 3 Trial (Sentinel Lymphoma)

Katell Le Dû, Adrien Chauchet, Sophie Sadot-Lebouvier, Olivier Fitoussi, Bijou Fontanet, Arnaud Saint-Lezer, Frédéric Maloisel, Cédric Rossi, Sylvain Carras, Anne Parcelier, Magali Balavoine, Anne-Lise Septans

JMIR Cancer 2025 (May 06); 11:e65960

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Effectiveness of an Innovative Mobile-Based Perioperative Care Program for Women Undergoing Breast Cancer Surgery (iCareBreast): Randomized Controlled Trial

Yan Pang, Honggu He, Ruey-Pyng Ng, Nicole Kim Luan Lee, Me Me Win Htein, Xiao-Xin Zhao, Ying-Hong Li, Elizabeth Jiahui Chan, Lixia Zhu, Guang Yu Liu, Minna Pikkarainen, Swee-Ho Lim

J Med Internet Res 2025 (Apr 21); 27:e71684

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Assessing Health Information Seeking Behaviors Among Targeted Social Media Users Using an Infotainment Video About a Cancer Clinical Trial: Population-Based Descriptive Study

Jonathan Sommers, Don S Dizon, Mark A Lewis, Erik Stone, Richard Andreoli, Vida Henderson

JMIR Cancer 2025 (Mar 03); 11:e56098

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Treatment Outcomes From Erlotinib and Gefitinib in Advanced Epidermal Growth Factor Receptor–Mutated Nonsquamous Non–Small Cell Lung Cancer in Aotearoa New Zealand From 2010 to 2020: Nationwide Whole-of-Patient-Population Retrospective Cohort Study

Phyu Sin Aye, Joanne Barnes, George Laking, Laird Cameron, Malcolm Anderson, Brendan Luey, Stephen Delany, Dean Harris, Blair McLaren, Elliott Brenman, Jayden Wong, Ross Lawrenson, Michael Arendse, Sandar Tin Tin, Mark Elwood, Philip Hope, Mark James McKeage

JMIR Cancer 2025 (Mar 03); 11:e65118

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