Clinical Cancer Research

Extracting Knowledge From Scientific Texts on Patient-Derived Cancer Models Using Large Language Models: Algorithm Development and Validation Study

Jiarui Yao, Zinaida Perova, Tushar Mandloi, Elizabeth Lewis, Helen Parkinson, Guergana Savova

JMIR Bioinform Biotech 2025 (Jun 30); 6:e70706

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Assessing the Efficacy of Current Histopathological Tumor Reporting Systems for Evaluating the Response to Neoadjuvant Chemotherapy for Breast Carcinoma: Protocol for an Observational Study

Anita Sajjanar, Sunita Vagha

JMIR Res Protoc 2025 (Jun 16); 14:e56825

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Barriers and Facilitators in Diagnostic Pathways That Align Universal Tumor Screening and Mainstream Genetic Testing for Lynch Syndrome in Colorectal Cancer: Protocol for a Scoping Review With a Narrative Synthesis

Linda Battistuzzi, Eva Blondeaux, Alberto Puccini, Luca Boni, Federica Grillo, Lucia Trevisan, Liliana Varesco, Maria Stefania Sciallero

JMIR Res Protoc 2025 (Jun 10); 14:e70831

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Co-Designing a User-Centered Digital Health Tool for Supportive Care Needs of Patients With Brain Tumors and Their Caregivers: Interview Analysis

Mahima Kalla, Ashleigh Bradford, Verena Schadewaldt, Kara Burns, Sarah C E Bray, Sarah Cain, Heidi McAlpine, Rana S Dhillon, Wendy Chapman, James R Whittle, Katharine J Drummond, Meinir Krishnasamy

JMIR Cancer 2025 (May 23); 11:e53690

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Patient Reactions to Artificial Intelligence–Clinician Discrepancies: Web-Based Randomized Experiment

Farrah Madanay, Laura S O'Donohue, Brian J Zikmund-Fisher

J Med Internet Res 2025 (May 22); 27:e68823

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Machine Learning for Predicting Postoperative Functional Disability and Mortality Among Older Patients With Cancer: Retrospective Cohort Study

Yuki Hashimoto, Norihiko Inoue, Takuaki Tani, Shinobu Imai

JMIR Aging 2025 (May 14); 8:e65898

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Primary Tumors of the Brain and Central Nervous System in Adults and Children in Sub-Saharan Africa: Protocol for a Scoping Review

Alhasan Ahmed Badeea Al-Fikri, Mesk Alhammadi, Chiedozie Arum, Mahima Kaur, Kayla Del Biondo, Ibrahim Bani, Victor Mudenda, Sten H Vermund

JMIR Res Protoc 2025 (Apr 24); 14:e66978

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The Fire Fighter Cancer Cohort Study: Protocol for a Longitudinal Occupational Cohort Study

Jefferey L Burgess, Shawn C Beitel, Miriam M Calkins, Melissa A Furlong, Paola Louzado Feliciano, Jamie Kolar Gabriel, Casey Grant, Jaclyn M Goodrich, Judith M Graber, Olivia Healy, James Hollister, Jeff Hughes, Sara Jahnke, Krystal Kern, Frank A Leeb, Alberto J Caban-Martinez, Alexander C Mayer, Russell Osgood, Cynthia Porter, Sreenivasan Ranganathan, Heather M Stapleton, Natasha Schaefer Solle, Christine Toennis, Derek J Urwin, Michelle Valenti, John J Gulotta

JMIR Res Protoc 2025 (Apr 22); 14:e70522

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Predicting Overall Survival in Patients with Male Breast Cancer: Nomogram Development and External Validation Study

Wen-Zhen Tang, Shu-Tian Mo, Yuan-Xi Xie, Tian-Fu Wei, Guo-Lian Chen, Yan-Juan Teng, Kui Jia

JMIR Cancer 2025 (Mar 04); 11:e54625

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Leveraging Patient-Reported Outcome Measures for Optimal Dose Selection in Early Phase Cancer Trials

Bill Byrom, Anthony Everhart, Paul Cordero, Chris Garratt, Tim Meyer

JMIR Cancer 2025 (Feb 28); 11:e64611

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Blended Care Intervention for Cancer Aftercare in General Practice Centers: Protocol for a Randomized Controlled Trial

Michelle J M Smits, Catherine A W Bolman, Ilse Mesters, Lilian Lechner

JMIR Res Protoc 2025 (Feb 12); 14:e64662

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Oncology Clinicians' Perspectives of a Remote Patient Monitoring Program: Multi-Modal Case Study Approach

Ann Marie Mazzella-Ebstein, Robert Daly, Jennie Huang, Camila Bernal, Clare Wilhelm, Katherine S Panageas, Jessie Holland, Rori Salvaggio, Jill Ackerman, Jennifer Cracchiolo, Gilad Kuperman, Jun Mao, Aaron Begue, Margaret Barton-Burke

JMIR Hum Factors 2025 (Jan 24); 12:e60585

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Telehomecare Monitoring for Patients Receiving Anticancer Oral Therapy: Protocol for a Mixed Methods Evaluability Study

Dominique Tremblay, Thomas Joly-Mischlich, Annick Dufour, Marie-Claude Battista, Djamal Berbiche, José Côté, Marco Décelles, Catherine Forget, Brigitte Guérin, Manon Larivière, Frédéric Lemay, Manon Lemonde, Éric Maillet, Nathalie Moreau, Michel Pavic, Sara Soldera, Catherine Wilhelmy

JMIR Res Protoc 2025 (Jan 20); 14:e63099

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Applications of Indocyanine Green in Breast Cancer for Sentinel Lymph Node Mapping: Protocol for a Scoping Review

Feryal Kurdi, Yahya Kurdi, Igor Vladimirovich Reshetov

JMIRx Med 2025 (Jan 06); 6:e66213

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Prehabilitation Exercise Training to Target Improved Muscle Strength in Pretransplant Patients Diagnosed With Multiple Myeloma: Protocol for a Pilot Randomized Controlled Trial

Amber J Normann, Clifton C Mo, Rebekah L Wilson, Michelle Perez, Corey Cutler, Hajime Uno, LaDora V Thompson, Tina L Skinner, Paul G Richardson, Catherine R Marinac, Christina M Dieli-Conwright

JMIR Res Protoc 2024 (Dec 19); 13:e64905

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Heuristics Identified in Health Data–Sharing Preferences of Patients With Cancer: Qualitative Focus Group Study

Anna Hermansen, Samantha Pollard, Kimberlyn McGrail, Nick Bansback, Dean A Regier

J Med Internet Res 2024 (Dec 17); 26:e63155

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Survival After Radical Cystectomy for Bladder Cancer: Development of a Fair Machine Learning Model

Samuel Carbunaru, Yassamin Neshatvar, Hyungrok Do, Katie Murray, Rajesh Ranganath, Madhur Nayan

JMIR Med Inform 2024 (Dec 13); 12:e63289

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Challenges and Approaches to Recruitment for and Retention in a Dyad-Focused eHealth Intervention During COVID-19: Randomized Controlled Trial

Chunxuan Ma, Rachel H Adler, Daria B Neidre, Ronald C Chen, Laurel L Northouse, Christine Rini, Xianming Tan, Lixin Song

J Med Internet Res 2024 (Dec 03); 26:e51877

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Ultrasound-Guided High-Intensity Focused Ultrasound Combined With PD-1 Blockade in Patients With Liver Metastases From Lung Cancer: Protocol for a Single-Arm Phase 2 Trial

Chao Hu, Qiang Fu, Fei Fei Gao, Jian Zeng, Wei Xiao, Hui Li, Li Peng, Xi Huang, Li Yang, Wen Zhi Chen, Ming Yan Jiang

JMIR Res Protoc 2024 (Nov 29); 13:e59152

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Efficacy and Safety of a Therapy Combining Sintilimab and Chemotherapy With Cryoablation in the First-Line Treatment of Advanced Nonsquamous Non–Small Cell Lung Cancer: Protocol for a Phase II, Pilot, Single-Arm, Single-Center Study

Zhiqiang Gao, Jiajun Teng, Rong Qiao, Jialin Qian, Feng Pan, Meili Ma, Jun Lu, Bo Zhang, Tianqing Chu, Hua Zhong

JMIR Res Protoc 2024 (Nov 08); 13:e64950

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