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The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

However, few human studies have experimentally manipulated maternal choline intake during pregnancy and assessed offspring cognition [24-26]. One such study evaluated the effect of providing pregnant women with either 900 mg/day of a choline supplement or a placebo from week 17 of gestation through birth and found a beneficial effect of the choline supplement on 5-month-old infants’ auditory attentional gating [17].

Sophie A Roth, Angie E Lam, Barbara J Strupp, Richard L Canfield, Elisabeth Anne Larson

JMIR Res Protoc 2025;14:e73508

Association Between COVID-19 During Pregnancy and Preterm Birth by Trimester of Infection: Retrospective Cohort Study Using Large-Scale Social Media Data

Association Between COVID-19 During Pregnancy and Preterm Birth by Trimester of Infection: Retrospective Cohort Study Using Large-Scale Social Media Data

To complement pregnancy registries [14], our previous work [15] has demonstrated that Twitter can also be used as a source of self-report data to assess the association between medication exposure during pregnancy and birth defects, including by trimester of exposure. Our ability to retrospectively collect users’ tweets enabled us to observe reports of exposures in the early stages of pregnancy—before prenatal care [16] and even knowledge of being pregnant—while reducing recall bias.

Ari Z Klein, Shriya Kunatharaju, Su Golder, Lisa D Levine, Jane C Figueiredo, Graciela Gonzalez-Hernandez

J Med Internet Res 2025;27:e66097

Development and Effect of Prenatal Education Programs Using Virtual Reality for Pregnant Women Hospitalized With Preterm Labor: Experimental Study

Development and Effect of Prenatal Education Programs Using Virtual Reality for Pregnant Women Hospitalized With Preterm Labor: Experimental Study

As there is no ideal treatment beyond bed rest and analgesics after the diagnosis of preterm labor, these women experience uncertainty regarding the maintenance of pregnancy and its prognosis [9,10]. Therefore, nurses should help minimize this confusion by providing knowledge related to pregnancy and preterm labor and by offering prenatal education to reduce psychological anxiety [9].

SeoA Park, Hyeyoung Kim

J Med Internet Res 2025;27:e75585

World Health Organization Evidence-Based Self-Help Plus Intervention for Stress Management via Chatbot: Protocol for Adaptation to a Tech-Enabled Model

World Health Organization Evidence-Based Self-Help Plus Intervention for Stress Management via Chatbot: Protocol for Adaptation to a Tech-Enabled Model

Pregnancy is characterized by major transformations in the woman, with an impact on her physical, mental, and social well-being. The literature shows that pregnant women experience various psychological symptoms, the most frequent being anxiety, stress, and depression [23]. Thus, women in the perinatal period may experience worries and the fear of being unable to manage the changes associated with the period and the baby or children yet to be born [24].

Valentina Fietta, Silvia Rizzi, Lorenzo Gios, Maria Chiara Pavesi, Chiara De Luca, Silvia Gabrielli, Merylin Monaro, Nicolò Navarin, Erik Gadotti, Oscar Mayora-Ibarra, Marianna Purgato, Corrado Barbui, Stefano Forti

JMIR Res Protoc 2025;14:e69644

COVID-19 Vaccine Uptake, Sources of Information and Side Effects Reported by Pregnant Women in Western Australia: Cross-Sectional Cohort Survey

COVID-19 Vaccine Uptake, Sources of Information and Side Effects Reported by Pregnant Women in Western Australia: Cross-Sectional Cohort Survey

Pregnancy puts women in a state of immune deficiency, and therefore increases vulnerability to infection [1], with unvaccinated pregnant women experiencing increased severity of symptoms and higher death rates compared to their vaccinated peers [2,4-6]. Along with increased risk of stillbirth, unvaccinated women also have an increased likelihood of premature birth and neonatal death if they contract SARS-Co V-2 virus during pregnancy [7,8].

Nicole Catalano, Shailender Mehta

JMIR Pediatr Parent 2025;8:e66645

The Effect of a Mobile App (eMOM) on Self-Discovery and Psychological Factors in Persons With Gestational Diabetes: Mixed Methods Study

The Effect of a Mobile App (eMOM) on Self-Discovery and Psychological Factors in Persons With Gestational Diabetes: Mixed Methods Study

The recent results of our randomized controlled trial (RCT) demonstrated that individuals with GDM who used e MOM improved their fasting glucose levels, enhanced physical activity, increased vegetable intake, and resulted in less weight gain during pregnancy [21]. Additionally, the incidence of newborns with macrosomia was lower among the individuals using e MOM [21].

Sini Määttänen, Saila Koivusalo, Hanna Ylinen, Seppo Heinonen, Mikko Kytö

JMIR Mhealth Uhealth 2025;13:e60855

Association of Self-Rated Health in Pregnancy With Maternal Childhood Experiences, Socioeconomic Status, Parity, and Choice of Antenatal Care Providers: Cross-Sectional Study

Association of Self-Rated Health in Pregnancy With Maternal Childhood Experiences, Socioeconomic Status, Parity, and Choice of Antenatal Care Providers: Cross-Sectional Study

Mental health issues are prevalent in pregnancy, with an American study estimating that approximately 12% of women experience a major depressive episode during pregnancy [25,26]. In Norway, over 9% of women report experiencing a postpartum depression [27]. While some studies suggest that mental health may remain stable or even improve during pregnancy [16], women with low social support are at an increased risk of developing mental health challenges [28].

Bjarne Austad, Gunnhild Åberge Vie, Mari Hegnes Hansen, Hanna Sandbakken Mørkved, Linn Okkenhaug Getz, Bente Prytz Mjølstad

JMIR Form Res 2025;9:e68811

Quality Assessment of Web-Based Information Related to Diet During Pregnancy in Pregnant Women: Cross-Sectional Descriptive Study

Quality Assessment of Web-Based Information Related to Diet During Pregnancy in Pregnant Women: Cross-Sectional Descriptive Study

Most women used the internet to access pregnancy-related information and found it beneficial [3]. Approximately 96% of pregnant women in Canada use the internet to find information about nutrition during pregnancy, with 75% reporting that they use the internet more often than any other source [4]. Women who are in their mid-20s to 30s, who were educated after high school, are employed, and are first-time mothers are more likely to obtain nutrition-related information from the internet [5].

Daichi Suzuki, Etsuko Nishimura, Rina Shoki, Ishak Halim Octawijaya, Erika Ota

JMIR Form Res 2025;9:e64630

The Effects of Acupoint Stimulation Combined With Transcutaneous Electrical Nerve Stimulation on Labor Pain: Protocol for a Stepped Wedge Cluster Randomized Controlled Trial

The Effects of Acupoint Stimulation Combined With Transcutaneous Electrical Nerve Stimulation on Labor Pain: Protocol for a Stepped Wedge Cluster Randomized Controlled Trial

Inclusion criteria require participants to have a singleton pregnancy with cephalic presentation, to be in good maternal and fetal health at admission, to plan to undergo a trial of labor, and to have no cognitive dysfunction or communication difficulties. Women with preexisting or pregnancy-related complications, as well as those with medical indications necessitating a cesarean section, are excluded from the study.

Yiyun Gu, Xiaojiao Wang, Chunxiang Zhu, Hui Min, Jialu Zhang, Liping Mao, Hua Gao, Hangyun Sun, Xinli Zhu, Chunyi Gu

JMIR Res Protoc 2025;14:e63050

Evaluating the Usability, Acceptability, User Experience, and Design of an Interactive Responsive Platform to Improve Perinatal Nurses’ Stigmatizing Attitudes Toward Substance Use in Pregnancy: Mixed Methods Study

Evaluating the Usability, Acceptability, User Experience, and Design of an Interactive Responsive Platform to Improve Perinatal Nurses’ Stigmatizing Attitudes Toward Substance Use in Pregnancy: Mixed Methods Study

Reference 4: Increase in prescription opioid use during pregnancy among Medicaid-enrolled women Reference 5: Patterns of opioid utilization in pregnancy in a large cohort of commercial insurance beneficiaries Reference 6: Recent trends in treatment admissions for prescription opioid abuse during pregnancy Reference 7: Prescription opioids in pregnancy and birth outcomes: a review of the literature Reference 31: Validity and reliability of the modified attitudes about drug use in pregnancy scalepregnancyInteractive Responsive Platform to Improve Perinatal Nurses’ Stigmatizing Attitudes Toward Substance Use in Pregnancy

Michael Rubyan, Yana Gouseinov, Mikayla Morgan, Deborah Rubyan, Divya Jahagirdar, David Choberka, Carol J Boyd, Clayton Shuman

JMIR Hum Factors 2025;12:e67685