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Effects of Therapeutic Ultrasound and Aussie Current With High-Intensity Interval Training on Abdominal Adiposity in Young Adults With Overweight and Obesity: Protocol for a Randomized Controlled Trial

Effects of Therapeutic Ultrasound and Aussie Current With High-Intensity Interval Training on Abdominal Adiposity in Young Adults With Overweight and Obesity: Protocol for a Randomized Controlled Trial

According to a report by the World Obesity Federation, more than half of the world’s population will be overweight or obese by 2035 [1]. Excess abdominal fat is a primary determinant for developing insulin resistance and other metabolic disorders [2]. Lifestyle modification is the most recommended approach for treating and preventing obesity at any stage of life [2].

Ana Carolina Aparecida Marcondes-Scalli, Patricia Rehder-Santos, Étore De Favari Signini, Alex Castro, Carla Dato, Leonardo Furlan, Richard Eloin Liebano, Aparecida Maria Catai

JMIR Res Protoc 2025;14:e71829

Effect of Minimal Individual or Group Enhancement in an eHealth Program on Mental Health, Health Behavior, and Work Ability in Employees With Obesity: Randomized Controlled Trial

Effect of Minimal Individual or Group Enhancement in an eHealth Program on Mental Health, Health Behavior, and Work Ability in Employees With Obesity: Randomized Controlled Trial

Obesity and mental health problems are intricately connected, with evidence suggesting a bidirectional relationship between the two [1,2]. Depression, one of the most extensively studied mental health issues, increases the risk of obesity by 58%, while obesity elevates the risk of depression by 55% [3]. Furthermore, both obesity and depression are significant risk factors for reduced work ability [4,5], and occupational burnout has been linked to these conditions [6-8].

Siniriikka A Männistö, Joona Muotka, Laura-Unnukka Suojanen, Raimo Lappalainen, Kirsi H Pietiläinen, Riitta Korpela

JMIR Ment Health 2025;12:e66518

A Remotely Delivered GLP-1RA–Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation

A Remotely Delivered GLP-1RA–Supported Specialist Weight Management Program in Adults Living With Obesity: Retrospective Service Evaluation

Obesity remains a global health crisis, affecting 890 million adults worldwide and contributing to diseases such as type 2 diabetes, cardiovascular disease, and certain cancers [1]. In the United Kingdom, projections suggest that by 2050, the annual cost of obesity to the National Health Service (NHS) could reach £9.7 billion (US $12.1 billion), with wider societal expenses approaching £49.9 billion (US $62.4 billion) [2].

Rebecca Richards, Michael Whitman, Gina Wren, Peta Campion

JMIR Form Res 2025;9:e72577

Virtual Reality in Obesity Management: Addressing Key Limitations in Clinical Application

Virtual Reality in Obesity Management: Addressing Key Limitations in Clinical Application

We are writing to express our appreciation for the recent publication in the Journal of Medical Internet Research titled “Assessing the Clinical Efficacy of a Virtual Reality Tool for the Treatment of Obesity: Randomized Controlled Trial” [1]. The authors propose an innovative approach to obesity treatment that leverages the interactivity and immersive experience of virtual reality (VR) technology through a randomized controlled trial, providing new scientific evidence for obesity management.

Xin Hu, Bin Wei

J Med Internet Res 2025;27:e68269

Community Health Worker Diabetes Prevention Awareness Training in an Immersive Virtual World Environment: Mixed Methods Pilot Study

Community Health Worker Diabetes Prevention Awareness Training in an Immersive Virtual World Environment: Mixed Methods Pilot Study

The burden of diabetes and obesity are greater for racial-ethnic minority groups in the United States, including non-Hispanic Blacks [1,2]. Estimates (2019‐2021) of the prevalence of diagnosed diabetes in the United States indicate that 12.5% of Black non-Hispanic adults (>18 years) have diabetes compared with 8.5% of white non-Hispanic adults [3]. Obesity is a major risk factor for the development of type 2 diabetes mellitus (T2 DM).

Laurie Ruggiero, Lauretta Quinn, Amparo Castillo, Colleen Monahan, Leticia Boughton Price, Wandy Hernandez

JMIR Form Res 2025;9:e64051

The Impact of Digital Technology–Based Exercise Combined With Dietary Intervention on Body Composition in College Students With Obesity: Prospective Study

The Impact of Digital Technology–Based Exercise Combined With Dietary Intervention on Body Composition in College Students With Obesity: Prospective Study

Over the past 4 decades, there has been a dramatic increase in obesity and related diseases, with approximately 50% of adults in China having overweight or obesity [1]. By 2030, the number of individuals with overweight or obesity in China is predicted to increase to 790 million, and the medical costs associated with overweight and obesity are expected to reach US $61 billion [2].

Chengyuan Hu, Zixin Lv, Jieping Zhu, Chunyuan Lai, Dongjuan Guo, Maolin Chen, Xiaoyan Cheng, Mingxin Rao, Xinyou Zhou, Liqiang Su

J Med Internet Res 2025;27:e65868

Leveraging Social Media Data to Understand the Impact of COVID-19 on Residents' Dietary Behaviors: Observational Study

Leveraging Social Media Data to Understand the Impact of COVID-19 on Residents' Dietary Behaviors: Observational Study

We obtained the state obesity rate data from the Behavioral Risk Factor Surveillance System (BRFSS). BRFSS provided the ground truth for the prevalence of obesity via self-reported obesity data among US adults by state and territory in 2019, 2020, and 2021. In Figure 3, we classified 49 states into 4 different obesity levels based on the state obesity rate. New Jersey was excluded from this study because the obesity rate data from BRFSS for New Jersey were missing due to insufficient data.

Chuqin Li, Alexis Jordan, Yaorong Ge, Albert Park

J Med Internet Res 2025;27:e51638

Evaluation of the Aspects of Digital Interventions That Successfully Support Weight Loss: Systematic Review With Component Network Meta-Analysis

Evaluation of the Aspects of Digital Interventions That Successfully Support Weight Loss: Systematic Review With Component Network Meta-Analysis

Obesity is a complex chronic disease associated with increased risks of developing life-limiting and life-threatening conditions, including cardiovascular disease, stroke, and type 2 diabetes [1]. It is a growing global health problem, with the number of obese adults across the world more than doubling since 1990 [2].

Michael Nunns, Samantha Febrey, Rebecca Abbott, Jill Buckland, Rebecca Whear, Liz Shaw, Alison Bethel, Kate Boddy, Jo Thompson Coon, G.J. Melendez-Torres

J Med Internet Res 2025;27:e65443

Evaluation of the Digital Support Tool Gro Health W8Buddy as Part of Tier 3 Weight Management Service: Observational Study

Evaluation of the Digital Support Tool Gro Health W8Buddy as Part of Tier 3 Weight Management Service: Observational Study

In the United Kingdom, 25% of men and 26% of women live with obesity [1]. Overweight and obesity are more prevalent in people living in the most deprived areas compared to the least deprived areas (72% and 58%, respectively) [1]. Similarly, excess weight disproportionately affects people in the Black ethnic group (72% compared to 64% in people from the White ethnic group) [1].

Petra Hanson, Farah Abdelhameed, Mohammed Sahir, Nick Parsons, Arjun Panesar, Michaela de la Fosse, Charlotte Summers, Amit Kaura, Harpal Randeva, Vinod Menon, Thomas M Barber

J Med Internet Res 2025;27:e62661

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

Obesity has reached pandemic proportions and is a major risk factor for type 2 diabetes (T2 D), cardiovascular disease, and other metabolic disorders. Prevention progression to T2 D in individuals with obesity through effective lifestyle interventions is a public health priority Substantial and sustained weight loss achieved through lifestyle modifications is a key strategy to reduce the risk of T2 D and improve metabolic health [1,2].

Monika Ludlova, Kateřina Koudelková, Jitka Pallova, Barbora Koudelkova, Michaela Siklova, Monika Cahova, Tomas Vetrovsky, Michal Steffl, Jan Gojda

JMIR Res Protoc 2025;14:e67570