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Effectiveness and Cost-Effectiveness of a Mobile Psychoeducation Program (OkeyMind) for Social Anxiety Symptoms Among Youths: Protocol for a Randomized Controlled Trial

Effectiveness and Cost-Effectiveness of a Mobile Psychoeducation Program (OkeyMind) for Social Anxiety Symptoms Among Youths: Protocol for a Randomized Controlled Trial

Okey Mind, a We Chat miniprogram, has a lower development complexity and shorter implementation cycle than a standalone mobile app, as it operates within the We Chat ecosystem, eliminating the need for separate app store approvals and extensive backend infrastructure [22,23].

Yi-Zhou Wang, De-Hui Ruth Zhou, Siu-Man Ng, Bei-Bei Wang, Yu-Ya Feng, Xue Weng

JMIR Res Protoc 2025;14:e64518

Bringing Executive Function Testing Online: Assessment Validation Study

Bringing Executive Function Testing Online: Assessment Validation Study

However, the timing varies considerably between the 2 tasks in that Freeze Frame utilizes a variable intertrial interval whereas SART has a consistent intertrial interval. The advantage of a variable time interval is that unlike consistent intertrial intervals, which increases attentional lapses and response anticipations [21], the unpredictable timing of the appearance of each image in Freeze Frame requires a more alert state and enhanced response control [22].

Mouna Attarha, Ana Carolina de Figueiredo Pelegrino, Lydia Ouellet, Sarah-Jane Grant, Etienne de Villers-Sidani, Thomas Van Vleet

JMIR Form Res 2025;9:e75687

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

One such study evaluated the effect of providing pregnant women with either 900 mg/day of a choline supplement or a placebo from week 17 of gestation through birth and found a beneficial effect of the choline supplement on 5-month-old infants’ auditory attentional gating [17].

Sophie A Roth, Angie E Lam, Barbara J Strupp, Richard L Canfield, Elisabeth Anne Larson

JMIR Res Protoc 2025;14:e73508

Patterns of Engagement With the mHealth Component of a Sexual and Reproductive Health Risk Reduction Intervention for Young People With Depression: Latent Trajectory Analysis

Patterns of Engagement With the mHealth Component of a Sexual and Reproductive Health Risk Reduction Intervention for Young People With Depression: Latent Trajectory Analysis

We undertook a secondary analysis of anonymized data collected from June 2021 to September 2023 in a randomized controlled trial of MARSSI versus a breast health podcast (Clinical Trials.gov NCT04798248).

Lydia A Shrier, Carly E Milliren, Brittany Ciriello, Madison M O'Connell, Sion Kim Harris

JMIR Mhealth Uhealth 2025;13:e70219

Effects of Therapeutic Ultrasound and Aussie Current With High-Intensity Interval Training on Abdominal Adiposity in Young Adults With Overweight and Obesity: Protocol for a Randomized Controlled Trial

Effects of Therapeutic Ultrasound and Aussie Current With High-Intensity Interval Training on Abdominal Adiposity in Young Adults With Overweight and Obesity: Protocol for a Randomized Controlled Trial

The experimental procedures for this analysis will follow those described in the work by De Favari Signini et al [34] and Castro et al [35]. To ensure the quality of the electrocardiogram (ECG) signal collection, the recommendations suggested by Catai et al [36] will be followed.

Ana Carolina Aparecida Marcondes-Scalli, Patricia Rehder-Santos, Étore De Favari Signini, Alex Castro, Carla Dato, Leonardo Furlan, Richard Eloin Liebano, Aparecida Maria Catai

JMIR Res Protoc 2025;14:e71829

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach

Increasingly, the internet and digital technologies hold a great promise to provide additional care and support for patients with and survivors of cancer [1]. A growing number of digital interventions have been developed and designed for patients with cancer living with and beyond a cancer diagnosis [2-7].

Carla Vlooswijk, Sophia HE Sleeman, Jonas Pluis, Daphne Bakker, Lisanne de Groot, Eveliene Manten, Peter Heine, Olga Husson, Mies C van Eenbergen, Pieter Vandekerckhove

JMIR Form Res 2025;9:e60897

Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study

Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study

Following the launch of the dashboard, we conducted a cross-sectional study targeting adults older than 18 years who lived or worked in Cayuga County using a 20-question online Qualtrics survey [20]. We conducted 2 phases of participant recruitment, resulting in a convenience sample. During the initial recruitment phase, spanning from May to August 2023, participants were offered a US $10 Amazon gift card as an incentive.

Zhongxuan He, Monika Salvage, Corinna A Noel

Online J Public Health Inform 2025;17:e68977

A Resource-Efficient, High-Dose, Gamified Neurorehabilitation Program for Chronic Stroke at Home: Retrospective Real-World Analysis

A Resource-Efficient, High-Dose, Gamified Neurorehabilitation Program for Chronic Stroke at Home: Retrospective Real-World Analysis

All patients were assigned to a single-arm treatment group involving a high-dose, home-based training program (Figure 1 A–B). For the purposes of this work, we consider a high-dose program to be one that achieves a total dosage above 20 hours scheduled time, as these doses are generally considered to deliver outcomes above the minimum clinically important difference [2,5,29]. Overall, the program goal was to deliver 36 hours of training during the program.

Spencer A Arbuckle, Anna Sophie Knill, Michelle H Chan-Cortés, Gabriela Rozanski, Anastasia Elena Ford, Louis T Derungs, John W Krakauer, Naveed Ejaz, David Putrino, Jenna Tosto-Mancuso, Meret Branscheidt

JMIR Serious Games 2025;13:e69335

AI Predictive Model of Mortality and Intensive Care Unit Admission in the COVID-19 Pandemic: Retrospective Population Cohort Study of 12,000 Patients

AI Predictive Model of Mortality and Intensive Care Unit Admission in the COVID-19 Pandemic: Retrospective Population Cohort Study of 12,000 Patients

The Hospital Universitario de Fuenlabrada (HUF) is the reference hospital for a population close to 220,000 inhabitants in the south of Madrid. This means that HUF is the only hospital where people from Fuenlabrada are admitted due to COVID-19. It has attended to more than 5000 hospitalized patients for COVID-19 with a mortality rate changing depending on the vaccination status and the SARS-Co V-2 variants. Massive vaccination campaigns have become the primary strategy against the pandemic.

Jose Manuel Ruiz Giardin, Óscar Garnica, Nieves Mesa Plaza, Juan Víctor SanMartín López, Ana Farfán Sedano, Elena Madroñal Cerezo, Miguel Ángel Duarte Millán, Aida Izquierdo Martínez, Luis Rivas, Marta Rivilla, Alejandro Morales Ortega, Begoña Frutos Pérez, Cristina De Ancos Aracil, Ruth Calderón, Guillermo Soria Fernandez, Jorge Marrero Francés, David Bernal Bello, Jose Ángel Satué Bartolomé, María Toledano Macías, Sara Piedrabuena García, Marta Guerrero Santillán, Rafael Cristóbal, Belen Mora, Laura Velázquez Ríos, Vanesa García de Viedma, Paula Cuenca Ruiz, Ibone Ayala Larrañaga, Lorena Carpintero, Celia Lara, Alvaro Ricardo Llerena, Virginia García Bermúdez, Gema Delgado Cárdenas, Paloma Pardo Rovira, Elena Tejero Sánchez, Maria Jesús Domínguez García, Carolina Mariño, Cristina Bravo, Ana Ontañon, Mario García, Jose Ignacio Hidalgo Pérez, Santiago Prieto Menchero, Natalia González Pereira, Sonia Gonzalo Pascua, Jorge Tarancón Rey, Luis Antonio Lechuga Suárez, FUENCOVID

J Med Internet Res 2025;27:e70674