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Authors’ Response to Peer Review of “Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study”

Authors’ Response to Peer Review of “Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study”

Table 2c’s description was amended to make this more clear: “d. Summary of the duration of time EDA and EOG features are collected from, across different experimental phases. For each phase—Baseline (before hand submersion), Cold Pressor Test (cold water immersion), and Recovery (after hand removal) —both tables list the minimum, 25th percentile, median, 75th percentile, and maximum duration (in seconds).”

Jadelynn Dao, Ruixiao Liu, Sarah Solomon, Samuel Aaron Solomon

JMIRx Med 2025;6:e77440

Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study

Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study

D. Another example of a blink peak, demonstrating the variability in blink peak shapes observed across recordings. The feature extraction process remains consistent, with boundaries determined by identifying the nearest minima on either side of the peak. EOG: electrooculography. However, wire movements can also produce peak-like shapes, which poses challenges for this filtering method.

Jadelynn Dao, Ruixiao Liu, Sarah Solomon, Samuel Aaron Solomon

JMIRx Med 2025;6:e69472

Association Between COVID-19 During Pregnancy and Preterm Birth by Trimester of Infection: Retrospective Cohort Study Using Large-Scale Social Media Data

Association Between COVID-19 During Pregnancy and Preterm Birth by Trimester of Infection: Retrospective Cohort Study Using Large-Scale Social Media Data

To assess the association between COVID-19 infection during pregnancy and preterm birth, we used the frequencies of these 2 categorical variables in a 2 × 2 contingency table to calculate the odds ratio (OR) with a 95% CI, where OR = (A/B) / (C/D) (Table 2).

Ari Z Klein, Shriya Kunatharaju, Su Golder, Lisa D Levine, Jane C Figueiredo, Graciela Gonzalez-Hernandez

J Med Internet Res 2025;27:e66097