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The target dose was consistent with a previous large telerehabilitation study that showed significant improvements in upper-limb impairment (42 h [29]). In contrast, training in this program was not limited to one body area [30-32] and could be achieved with multiple effectors (ie, upper-limb, hand, trunk, and lower-limb).
Training dose was delivered via synchronous telerehabilitation and asynchronous training (Table 2).
JMIR Serious Games 2025;13:e69335
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Participants received the HWC e Health program (as detailed in item 1) and participated in 3 remotely facilitated group meetings via video (each lasting 2 h). Due to the COVID-19 pandemic, these meetings were held remotely and included brief introductions to topics, such as goal setting, stress management, and self-compassion, followed by small-group discussions (Table S2 in Multimedia Appendix 1). Group meetings were held at 1, 6, and 10 months during the 12-month treatment period.
JMIR Ment Health 2025;12:e66518
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RF AUROCh=0.691 (95% CI 0.671-0.711)
DNN AUROC=0.691 (95% CI 0.671-0.712)
Ada Boost AUROC=0.653 (95% CI 0.632-0.674)
AUROC=0.824 (95% CI 0.814-0.834)
AUROC=0.720
C-index: 0.788 (compared to 0.730 for German Vasc Score)
Sensitivity=50%
Specificity=90%
AUROC=0.88-0.90
AUROC of 0.88, 0.84, and 0.83 for sepsis onset and 24 and 48 h before onset, respectively
AUROC=0.74
Specificity=98.7%
RF AUROC=0.742
SVM AUROC=0.675
XGBoost AUROC=0.745
LR AUROC=0.669
AUC of 0.67, 0.65, 0.78, and 0.73 for per‐patient, LADt, LCxu,
JMIR Med Inform 2025;13:e68898
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