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Trastuzumab (Herceptin), a human epidermal growth factor receptor 2 (HER2) antibody, has had a major impact on the treatment of patients with HER2-positive breast cancer (BC) worldwide, which now has indications for the treatment of small tumors in both (neo)adjuvant and palliative settings [3,4]. This provides a good opportunity to compare the efficacy and safety of trastuzumab biosimilars to those of trastuzumab in clinical trials.
JMIR Cancer 2024;10:e54178
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