Search Articles

View query in Help articles search

Search Results (1 to 10 of 165 Results)

Download search results: CSV END BibTex RIS


Impact of Tai Chi Therapy on Fatigue and Cognitive Function in Individuals With Chronic Fatigue Syndrome: Protocol for a Pilot Randomized Controlled Trial

Impact of Tai Chi Therapy on Fatigue and Cognitive Function in Individuals With Chronic Fatigue Syndrome: Protocol for a Pilot Randomized Controlled Trial

In recent years, exercise therapy has emerged as a research hot spot in CFS treatment, showing notable benefits in symptom improvement. Traditional Qigong, in particular, offers several advantages, including the regulation of the body, breath, and mind. Previous studies [17,18] have shown that Qigong can relieve both overall fatigue and psychological fatigue, making it an effective treatment for CFS.

Bin Wang, Xiaodong Zhang, Ping Lu, Pingping Sun, Tianxiang He

JMIR Res Protoc 2025;14:e65958

Expert and Interdisciplinary Analysis of AI-Driven Chatbots for Mental Health Support: Mixed Methods Study

Expert and Interdisciplinary Analysis of AI-Driven Chatbots for Mental Health Support: Mixed Methods Study

Wysa, on the other hand, is explicitly presented as a “clinically validated AI” capable of engaging people in “warm and friendly conversations” informed by “cognitive-behavioral techniques dialectical behavioral therapy, meditation, breathing, yoga, motivational interviewing, and microactions to help you build mental resilience skills and feel better” [37]. As of 2024, Wysa makes clear its limitations, stating it cannot help in crisis or in cases of severe mental health concerns [44].

Kayley Moylan, Kevin Doherty

J Med Internet Res 2025;27:e67114

Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Consequently, behavioral and psychological interventions, such as cognitive behavioral therapy for insomnia (CBT-I) [15] and mindfulness [16,17], have gained popularity for treating sleep disturbances and insomnia, with a robust body of literature supporting their efficacy [15-18].

Walter Staiano, Christine Callahan, Michelle Davis, Leah Tanner, Chelsea Coe, Sarah Kunkle, Ulrich Kirk

JMIR Mhealth Uhealth 2025;13:e68665

The Efficacy of Digital Interventions on Adherence to Oral Systemic Anticancer Therapy Among Patients With Cancer: Systematic Review and Meta-Analysis

The Efficacy of Digital Interventions on Adherence to Oral Systemic Anticancer Therapy Among Patients With Cancer: Systematic Review and Meta-Analysis

Oral systemic anticancer therapy (SACT) has become increasingly accessible over the past 10 years, comprising 25% of oncology prescriptions globally [8] due to the advantages of being noninvasive, less intrusive, and more convenient [9]. However, they are prone to nonadherence as patients take medicines away from the medical setting. Many patients struggle to adhere to daily oral SACTs, with an adherence rate varying from 16% to 100% based on the settings and types of medicine [10].

Wan-Chuen Liao, Fiona Angus, Jane Conley, Li-Chia Chen

JMIR Cancer 2025;11:e64208

Exploring Technical Features to Enhance Control in Videoconferencing Psychotherapy: Quantitative Study on Clinicians’ Perspectives

Exploring Technical Features to Enhance Control in Videoconferencing Psychotherapy: Quantitative Study on Clinicians’ Perspectives

More precisely, VCP improves psychotherapy accessibility by providing a flexible and cost-effective alternative to FTF therapy [33-35], but it also gives rise to technical and relational concerns from psychologists’ perspectives [32]. Certainly, COVID-19 forced psychologists to be more exposed to VCTs, reducing some of their technical concerns over time.

Francesco Cataldo, Shanton Chang, Antonette Mendoza, George Buchanan, Nicholas Van Dam

J Med Internet Res 2025;27:e66904

Perspectives on and Experiences With Remote Monitoring and Patient-Initiated Care Among Norwegian Patients With Axial Spondyloarthritis: Qualitative Study

Perspectives on and Experiences With Remote Monitoring and Patient-Initiated Care Among Norwegian Patients With Axial Spondyloarthritis: Qualitative Study

A flare is generally considered an increase in disease activity that may necessitate a change or intensification of therapy [5]. Consequently, the management of ax Sp A requires frequent and lifelong monitoring and treatment [6]. Some patients with ax Sp A use disease-modifying antirheumatic drugs, such as tumor necrosis factor inhibitors, and receive long-term follow-up in specialist health care with assessments of treatment efficacy [7,8].

Christine Hillestad Hestevik, Cecilie Varsi, Nina Østerås, Anne Therese Tveter, Jon Skandsen, Hedda Eik

J Med Internet Res 2025;27:e63569

Assessing the Data Quality Dimensions of Partial and Complete Mastectomy Cohorts in the All of Us Research Program: Cross-Sectional Study

Assessing the Data Quality Dimensions of Partial and Complete Mastectomy Cohorts in the All of Us Research Program: Cross-Sectional Study

An alternative to a complete mastectomy is breast-conserving therapy (BCT), which consists of breast-conserving surgery and radiation therapy [4]. In multiple randomized controlled trials, BCT has been shown to have similar long-term disease-free survival to a complete mastectomy [5-8]. A recent systematic review found that patients’ choice of surgical treatment was multifaceted.

Matthew Spotnitz, John Giannini, Yechiam Ostchega, Stephanie L Goff, Lakshmi Priya Anandan, Emily Clark, Tamara R Litwin, Lew Berman

JMIR Cancer 2025;11:e59298

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial

Sacubitril and valsartan, β-blockers, mineralocorticoid receptor antagonists (MRAs), and SGLT2is are disease-modifying agents that are used as combination therapy and are now regarded as a foundational therapy for HFr EF [1,2]. The conventional approach to initiating and optimizing HFr EF therapy reflects the sequence in which drugs were developed and trialed over the past 40 years [1].

Sumanth Karamchand, Tsungai Chipamaunga, Poobalan Naidoo, Kiolan Naidoo, Virendra Rambiritch, Kevin Ho, Robert Chilton, Kyle McMahon, Rory Leisegang, Hellmuth Weich, Karim Hassan

JMIR Res Protoc 2025;14:e44027

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

In addition, outpatient therapy is not feasible for many patients because of the high costs of individual specialized therapies and the logistical difficulties of transportation from or to the hospital. Home rehabilitation is a good option to continue recovery from chronic diseases such as stroke and a good alternative to manage long-term rehabilitation problems.

Margherita Rampioni, Sara Leonzi, Luca Antognoli, Anna Mura, Vera Stara

J Med Internet Res 2025;27:e57957

Advancing Clinical Chatbot Validation Using AI-Powered Evaluation With a New 3-Bot Evaluation System: Instrument Validation Study

Advancing Clinical Chatbot Validation Using AI-Powered Evaluation With a New 3-Bot Evaluation System: Instrument Validation Study

Artificial intelligence (AI) automation in low- to mid-level tasks like patient education and initial therapy screening emerges as a strategic response to mitigate this shortage, reallocating medical staff to higher-priority tasks [2,3]. The advent of advanced multimodal large language models (LLMs) such as GPT-4 introduces a paradigm shift, promising scalable, cost-effective chatbot solutions, which are particularly helpful for tasks that require the provider to interact with the patient [4].

Seungheon Choo, Suyoung Yoo, Kumiko Endo, Bao Truong, Meong Hi Son

JMIR Nursing 2025;8:e63058