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Investigating Challenges in Implementing a Digital Play Intervention in a Complex Organization Across Pediatric Departments: Non-Randomized Controlled Feasibility Trial

Investigating Challenges in Implementing a Digital Play Intervention in a Complex Organization Across Pediatric Departments: Non-Randomized Controlled Feasibility Trial

A recent review of game technologies for pediatric patients showed that the most common approach is mono-user games on ordinary computers or video consoles, for example, Play Station and Nintendo Wii, that often serve to distract children undergoing procedures such as venipuncture or who experience chronic, neurological, or traumatic diseases or injuries [1].

Laerke Winther, Michelle Stahlhut, Derek John Curtis, Christian Have Dall, Thomas Leth Frandsen, Jette Led Sorensen

JMIR Rehabil Assist Technol 2025;12:e58019

Validation and Comparison of Pediatric Appendicitis Scores and Management Strategies (Project SPASMS): Protocol for a Prospective Multicenter Observational Study

Validation and Comparison of Pediatric Appendicitis Scores and Management Strategies (Project SPASMS): Protocol for a Prospective Multicenter Observational Study

The most frequently used CPSs in children are the Alvarado score [2], the Pediatric Appendicitis Score (PAS) [3], and the pediatric appendicitis risk calculator (p ARC) [4], with each based on different sets of collected variables. The Alvarado score is one of the most widely studied CPSs for the diagnosis of acute appendicitis in adult populations based on 8 variables with a total score of 10 [2], and it has since been studied in pediatric populations with varying results [33-44].

Wei Hao Lee, Sharon O'Brien, Elizabeth J Mckinnon, Simon Craig, Stuart Dalziel, Michael Collin, Natalie Phillips, Franz E Babl, Sarah Julia Davidson, Shane George, Shefali Jani, Doris Tham, Viet Tran, Meredith L Borland

JMIR Res Protoc 2025;14:e67941

Efficacy of Solifenacin, Mirabegron, and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry): Protocol for a Randomized Single-Blinded Controlled Trial

Efficacy of Solifenacin, Mirabegron, and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry): Protocol for a Randomized Single-Blinded Controlled Trial

Solifenacin and mirabegron are widely used off-label in the pediatric population, and only a few studies have dealt with the efficacy and tolerability of these agents [10-14]. Only 1 study has evaluated combination therapy [14]. Since the pharmacological approach is widely used off-label in pediatric departments, an evidence-based treatment approach of pharmacological therapy is highly needed.

Ann-Kristine Mandøe Svendsen, Søren Hagstrøm, Kristina Thorsteinsson, Jason Van Batavia, Konstantinos Kamperis, Anne Estrup Olesen, Luise Borch

JMIR Res Protoc 2025;14:e63588

Association Between the Parenting Competence and Quality of Life of Family Caregivers of Children Aged 0-3 Years: Cross-Sectional Study

Association Between the Parenting Competence and Quality of Life of Family Caregivers of Children Aged 0-3 Years: Cross-Sectional Study

Reference 30: Health-related quality of life in pediatric patients with syndromic autism and their caregiverspediatricCaregiving and Parenting for Chronic Pediatric Diseases

Wei He, Le-shan Zhou, Long-yi Hu

JMIR Pediatr Parent 2025;8:e67872

Piloting the Extension for Community Healthcare Outcomes (ECHO) Pediatric Oncology Telehealth Education Program in Western Kenya: Implementation Study

Piloting the Extension for Community Healthcare Outcomes (ECHO) Pediatric Oncology Telehealth Education Program in Western Kenya: Implementation Study

However, in the past 3 years, an average of only 216 pediatric patients were diagnosed with cancer annually [5]. This suggests that the remaining 75%‐80% of patients remain undiagnosed and likely do not survive (Figure 1). One example is pediatric leukemia, the most common type of pediatric cancer in this region. Although this malignancy should represent 300‐480 cases (ie, 30%‐40% of all pediatric cancer diagnosis), only 40 cases per year have been seen over the last several years [5].

Tyler Severance, Gilbert Olbara, Festus Njuguna, Martha Kipng'etich, Sandra Lang'at, Maureen Kugo, Jesse Lemmen, Marjorie Treff, Patrick Loehrer, Terry Vik

JMIR Form Res 2025;9:e59776

Supporting Medication Adherence in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplant Using the BMT4me mHealth App: Mixed Methods Usability Study

Supporting Medication Adherence in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplant Using the BMT4me mHealth App: Mixed Methods Usability Study

Pediatric hematopoietic stem cell transplants (HCTs) are an intensive life-saving treatment for several malignant and nonmalignant disorders [1]. However, HCT often requires a long hospital stay that is stressful for the children and their caregivers [2]. Symptom and medication management are important components of the HCT experience, and it is critical for caregivers to adhere to recommendations and communicate with the care team [3].

Mariam Kochashvili, Parishma Guttoo, Emre Sezgin, Ahna Pai, Rajinder Bajwa, Wendy Landier, Cynthia Gerhardt, Micah Skeens

JMIR Cancer 2025;11:e66847