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Osteosarcoma is a primary malignancy of the bone, affecting 3.4 million individuals globally each year, and is the third most common cancer in the adolescent population [1]. The current treatment for osteosarcoma consists of complete surgical resection coupled with neoadjuvant and adjuvant chemotherapy. Though the introduction of adjuvant chemotherapy in the 1970s has greatly improved survival [2], the diagnosis of osteosarcoma is a significant, life-altering event for patients.
JMIR Cancer 2022;8(1):e25005
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Treatment outcomes for patients diagnosed during adolescence and young adulthood with the most common bone sarcomas, osteosarcoma (OS), and Ewing sarcoma have improved over the past 30 years with the evidence-based introduction of intensive chemotherapy, wide-margin surgery, and, for some, radiation treatment [1-5]. The 5-year survival rate has improved especially for patients aged younger than 25 years [6].
JMIR Res Protoc 2019;8(9):e14406
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