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Reprinted with permission from Meng et al [6].
Within these modules, several parameters are available in the code that allow the adjustment and introduction of special cases and exceptions for the rules. Common adjustments relate to the detection of maintenance therapy, checking for drug switches early in a LOT, and adding exceptions to line advancement for gaps in therapy or when certain drug classes are added or substituted in a treatment regimen.
JMIR Med Inform 2021;9(10):e29017
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