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Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study)

Blood pressure in mm Hg Pulse frequency per minute Waist (in cm)/hip (in cm) ratio BMI in kg/m2 BMDb values in g/cm2 T and Z scores Presence of osteopenia (defined as T-scores of −1 to −2.5) Presence of osteoporosis (defined as T-scores of ≥−2.5) Vertebral height reduction in percentage Presence of clinical and nonclinical vertebral fractures Bone formation by P1 NPc, mean value in ng/m L Bone resorption by β-CTXd, mean value in pg/m L Level of 25-hydroxyvitamin D in the serum in nmol/L Verbal memory Attention Executive

Lara Terra, Maartje J Hooning, Bernadette A M Heemskerk-Gerritsen, Marc van Beurden, Jeanine E Roeters van Lennep, Helena C van Doorn, Joanne A de Hullu, Constantijne Mom, Eleonora B L van Dorst, Marian J E Mourits, Brigitte F M Slangen, Katja N Gaarenstroom, M Carola Zillikens, Tim Leiner, Lizet van der Kolk, Margriet Collee, Marijke Wevers, Margreet G E M Ausems, Klaartje van Engelen, Lieke PV Berger, Christi J van Asperen, Encarna B Gomez-Garcia, Irma van de Beek, Matti A Rookus, Michael Hauptmann, Eveline M Bleiker, Sanne B Schagen, Neil K Aaronson, Angela H E M Maas, Flora E van Leeuwen