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Identifying this common ancestor can in turn lead to the identification of numerous n-degree relatives and opportunities for prevention through cascade testing. Traditionally, relatives who would benefit from cascade testing are identified through 3-generation pedigrees created by genetic professionals, and many studies have used this principle to connect families through rare disease mutations, creating very large multigenerational pedigrees [18-22]. However, there is a missed opportunity.
JMIR Cancer 2023;9:e43126
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