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A Health Service Research Study on a Low-Threshold Hearing Screening Program for Childhood Cancer Survivors in Switzerland: Protocol for the HEAR Study

Philippa Jörger, Carina Nigg, Luzius Mader, Sven Strebel, Martin Kompis, Zuzana Tomášiková, Christina Schindera, Gisela Michel, Nicolas Xavier von der Weid, Marc Ansari, Nicolas Waespe, Claudia Elisabeth Kuehni

JMIR Res Protoc 2025;14:e63627

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Assessing Pulmonary Function in Children and Adolescents After Cancer Treatment: Protocol for a Multicenter Cohort Study (Swiss Childhood Cancer Survivor Study FollowUp–Pulmo)

To determine the sample size needed for our study, we based calculations on the study by Schindera et al [22], who assessed lung function in long-term CCS using spirometry and N2 MBW. This single-center study was conducted on Swiss CCS and applied the same inclusion criteria for treatment exposures, making it a suitable reference. The main outcome from N2 MBW was the lung clearance index (LCI). The mean LCI z-score was 1.37 (SD 2.69).

Maša Žarković, Christina Schindera, Grit Sommer, Christine Schneider, Jakob Usemann, Maria Otth, Sonja Lüer, Marc Ansari, Philipp Latzin, Claudia E Kuehni