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Dermatologic Data From the Global Burden of Disease Study 2019 and the PatientsLikeMe Online Support Community: Comparative Analysis

Dermatologic Data From the Global Burden of Disease Study 2019 and the PatientsLikeMe Online Support Community: Comparative Analysis

Nonparametric Spearman correlations (R version 4.2.2; R Core Team) were used to assess the correlation of GBD prevalence and morbidity with PLM user numbers (statistical significance: 2-tailed P All research complied with regulations for the protection of human subjects under 45 CFR 46.104(d) (4), using publicly available data without requiring additional contact or permissions from content creators.

Mindy D Szeto, Lina Alhanshali, Chandler W Rundle, Madeline Adelman, Michelle Hook Sobotka, Emily Woolhiser, Jieying Wu, Colby L Presley, Jalal Maghfour, John Meisenheimer, Jaclyn B Anderson, Robert P Dellavalle

JMIR Dermatol 2024;7:e50449

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From the Cochrane Library: Interventions for Chronic Pruritus of Unknown Origin

From the Cochrane Library: Interventions for Chronic Pruritus of Unknown Origin

Pregabalin is considered to alleviate CPUO through modulating thresholds of the C-fibers shown to transmit itch signals by suppressing the release of several neurotransmitters such as substance P, which may be chronically elevated in patients with CPUO [4]. Dupilumab, which can inhibit interleukin (IL)-4 and IL-13, with well-known anti-inflammatory properties, may help to alleviate CPUO through cytokine-neural interactions [3].

Pritika Parmar, Amit Singal, Mindy D Szeto, Gaurav N Pathak, Viktoria Taranto, Thu M Truong, Babar Rao, Andrea Andrade Miranda, Juan VA Franco, Robert P Dellavalle

JMIR Dermatol 2024;7:e53271

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Nutrition, Obesity, and Seborrheic Dermatitis: Systematic Review

Nutrition, Obesity, and Seborrheic Dermatitis: Systematic Review

They found that the Western diet, characterized by meat, potato, and alcohol consumption, was associated with a higher risk for seborrheic dermatitis (adjusted odds ratio 1.34; P=.07) but only in female patients [16]. They also found that an increased amount of fruit in the diet was associated with a lower risk of seborrheic dermatitis (adjusted odds ratio 0.75; P=.03) [16].

Emily Woolhiser, Noah Keime, Arya Patel, Isaac Weber, Madeline Adelman, Robert P Dellavalle

JMIR Dermatol 2024;7:e50143

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