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The PMIS (Pearson r=−0.76; P
As we examined the sensitivity and specificity data to choose cut scores, we chose to favor sensitivity to minimize missing individuals with true disease in this sample of patients considered high risk because of their cognitive concerns. The cut scores for a positive result on the 5-Cog components were as follows: PMIS ≤6 (range 0-8), Symbol Match ≤25 (range 0-65), and s MCR >5 (range 0-7).
JMIR Res Protoc 2025;14:e60471
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Implemented as R (The R Foundation for Statistical Computing) and Python (Python Software Foundation) code routines, the LOT algorithm uses a modular design to facilitate plug-and-play tumor-specific customization. The LOT algorithm along with tumor-specific customizations is available as open-source software through Git Hub [19].
JMIR Med Inform 2021;9(10):e29017
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