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Shah et al looked at over 8000 individuals with sickle cell disease over a 3-year period and reported that each patient averaged 3.3 VOCs per year [6].
VOCs are associated with a decreased health-related quality of life and are a significant morbidity for individuals with sickle cell disease; it is the most common cause of hospitalization in SCD [5,7]. The treatment for VOCs is currently limited to analgesics such as opioids, which are given in proportion to the reported level of pain [8].
JMIR Form Res 2023;7:e45355
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