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Advancing Real-World Evidence Through a Federated Health Data Network (EHDEN): Descriptive Study
Any organization with access to a data source in Europe could apply to be included in the EHDEN network. In this context, a data source is defined as a distinct repository of health care-related data pertaining to a specific set of individuals. Except for the COVID-19 Rapid Collaboration Call, the 7 DP calls executed between September 2019 and October 2022 were aligned to similar timelines for DP identification, grant awarding, and initiation of data harmonization (Figure 1).
J Med Internet Res 2025;27:e74119
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Virtual Reality for Pediatric Postoperative Pain Management: Exploring Methods and Efficacy
In a single-center, prospective, pilot study, Olbrecht et al [15] provided a single VR-D session to 50 children after surgery, providing them the option to play 1 of several VR games.
J Med Internet Res 2025;27:e68348
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Data collection did not focus on a specific clinical setting. Veterans invited to the cohort were active users of VHA health care and technology users, defined as owning a cellular phone and having sent ≥5 secure messages through My Healthe Vet in the previous year [26,27].
VET-C surveys were collected between 2017-2018, 2019-2020, and 2021-2022.
JMIR Form Res 2025;9:e77113
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Virtual reality (VR) is a technology that provides an immersive experience of a computer-generated, 3 D image or environment using a head-mounted display. VR has presented a low-risk way to interrupt the brain’s “default mode network” (DMN), which is a particular set of brain structures that underlie the negative mental states marked by worry, rumination, and stress [15-18].
JMIR Cardio 2025;9:e66557
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Emerging evidence suggests a potential variation in the natural history of IC/BPS across racial and ethnic groups. For instance, Black individuals with IC/BPS report a greater degree of urinary urgency compared to their White counterparts and are more likely to be diagnosed at a younger age [19,20].
JMIR Form Res 2025;9:e70813
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Survival rates for most types of childhood cancers have fortunately risen to over 80%, resulting in a growing cohort of nearly half a million childhood cancer survivors in the United States [1]. However, life-saving cancer treatments, such as chemotherapy and radiation, can be detrimental to a child’s development and lead to a host of chronic health needs for up to two-thirds of survivors, termed late effects [1].
JMIR Pediatr Parent 2025;8:e70055
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The Ca RISMA trial enrolled adults with SCD who reported chronic pain (ie, pain at least 4 days a week over the past 3 months or longer). Participants of the Ca RISMA trial were recruited from 7 comprehensive sickle cell centers and from 4 community-based organizations, either virtually or in person. Participants were randomized 1:1 to either the digital CBT or Education arm. Both arms had access to a health coach and a chat system via a chatbot.
JMIR Hum Factors 2025;12:e73719
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Role and Use of Race in Artificial Intelligence and Machine Learning Models Related to Health
The role and use of the social construct of race within health-related artificial intelligence (AI) and machine learning (ML) models have become a subject of increased attention and controversy. As noted in the National Academies’ recent report “Ending Unequal Treatment,” it is increasingly clear that race in all its complexity is a powerful predictor of unequal treatment and health care outcomes [1].
J Med Internet Res 2025;27:e73996
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Hypertension has remained a public health concern in the American adult population. Hypertension, defined as systolic blood pressure (BP) ≥130 mm Hg or diastolic BP ≥80 mm Hg or both, has a prevalence of 46.7%, and control (systolic BP
Over the years, several models and scales of e-HL have been proposed to measure e-HL [6-20]. There is currently no gold standard for e-HL measurement.
J Med Internet Res 2025;27:e71926
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This might lead to a potential bias if recordings of both classes were done in different rooms (ie, recording participants with depression in a clinic and those with depression in an office or studio) as room acoustics have a significant impact on voice recordings [18].
JMIR Res Protoc 2025;14:e60439
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