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Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Power analyses were focused on the ability to detect a medium effect size (Cohen d=0.50) at postcondition in the context of a 2-level random coefficients HLM. Given that the primary contrast of interest would be that between CBI and the other study conditions, calculations were focused on detecting significant differences between two active conditions. Where study parameters in this 2-level model were not yet known, we used standard values and varied parameters to approximate an effective sample size.

Noah Robinson, Francisco N Ramos, Steven D Hollon, Gloria T Han, Iony D Ezawa

JMIR Res Protoc 2025;14:e65970

Virtual Versus In-Person Intensive Outpatient Treatment for Eating Disorders During the COVID-19 Pandemic in United States–Based Treatment Facilities: Naturalistic Study

Virtual Versus In-Person Intensive Outpatient Treatment for Eating Disorders During the COVID-19 Pandemic in United States–Based Treatment Facilities: Naturalistic Study

Cohen d effect sizes for all effects irrespective of statistical significance are reported and interpreted as small (d≥0.3), medium (d≥0.5), and large (d≥0.8) [33]. Odds ratios and 95% CIs are presented for logistic regression results.

Dan V Blalock, Philip S Mehler, Deborah M Michel, Alan Duffy, Daniel Le Grange, Anne M O'Melia, Renee D Rienecke

J Med Internet Res 2025;27:e66465

Neuromuscular Electrical Stimulation to Maximize Hip Abductor Strength and Reduce Fall Risk in Older Veterans: Protocol for a Randomized Controlled Trial

Neuromuscular Electrical Stimulation to Maximize Hip Abductor Strength and Reduce Fall Risk in Older Veterans: Protocol for a Randomized Controlled Trial

Before accepting the results of the model, we will make sure the results conform to the assumptions of the model (eg, reviewing residual plots), and we will make sure that no observation has undue influence on the estimates produced by the model (eg, Cook D). We will conduct exploratory analyses to examine relationships among variables and their changes in response to the intervention.

Ben Friedman, Brock A Beamer, Jeffrey Beans, Vicki Gray, Gad Alon, Alice Ryan, Leslie I Katzel, John D Sorkin, Odessa Addison

JMIR Res Protoc 2025;14:e68082

Technology-Based HIV Prevention Interventions for Men Who Have Sex With Men: Systematic Review and Meta-Analysis

Technology-Based HIV Prevention Interventions for Men Who Have Sex With Men: Systematic Review and Meta-Analysis

A meta-analysis of e Health interventions among men who have sex with men found a small but significant effect size for all 3 behavioral outcomes over the reviewed study period: any condomless anal intercourse with nonpaying male partners (Cohen d=−0.21; P We aimed to describe technology-based HIV prevention interventions among men who have sex with men and transgender women in China, document the intervention strategies, estimate intervention effects, and explore the relationships between intervention features

Wenting Huang, Daniel Stegmueller, Jason J Ong, Susan Schlueter Wirtz, Kunru Ning, Yuqing Wang, Guodong Mi, Fei Yu, Chenglin Hong, Jessica M Sales, Yufen Liu, Stefan D Baral, Patrick S Sullivan, Aaron J Siegler

J Med Internet Res 2025;27:e63111