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The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

One such study evaluated the effect of providing pregnant women with either 900 mg/day of a choline supplement or a placebo from week 17 of gestation through birth and found a beneficial effect of the choline supplement on 5-month-old infants’ auditory attentional gating [17].

Sophie A Roth, Angie E Lam, Barbara J Strupp, Richard L Canfield, Elisabeth Anne Larson

JMIR Res Protoc 2025;14:e73508

Patterns of Engagement With the mHealth Component of a Sexual and Reproductive Health Risk Reduction Intervention for Young People With Depression: Latent Trajectory Analysis

Patterns of Engagement With the mHealth Component of a Sexual and Reproductive Health Risk Reduction Intervention for Young People With Depression: Latent Trajectory Analysis

We undertook a secondary analysis of anonymized data collected from June 2021 to September 2023 in a randomized controlled trial of MARSSI versus a breast health podcast (Clinical Trials.gov NCT04798248).

Lydia A Shrier, Carly E Milliren, Brittany Ciriello, Madison M O'Connell, Sion Kim Harris

JMIR Mhealth Uhealth 2025;13:e70219

Measuring Stress Reduction in Patients Receiving Multimedia Entertainment During Vascular Surgery Under Regional Anesthesia: Protocol for a Randomized Controlled Study

Measuring Stress Reduction in Patients Receiving Multimedia Entertainment During Vascular Surgery Under Regional Anesthesia: Protocol for a Randomized Controlled Study

This approach offers the advantage of monitoring for neurological changes during carotid artery clamping, allowing the surgical team to immediately respond, for example, by placing a shunt system to ensure cerebral antegrade perfusion [4]. As a result, regional anesthesia provides a benefit during surgery. However, for patients, the procedure, which can last up to 2 hours or more in some cases, may pose a significant burden.

Hagen Kerndl, Thomas Peter Millian, Karlheinz Gürtler, Alexander Hyhlik-Duerr

JMIR Res Protoc 2025;14:e70597

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach

Developing and Integrating Digital Sources in an Accessible and Sustainable Online Platform for Adolescents and Young Adult Cancer Survivors: Collaborative Design Approach

Increasingly, the internet and digital technologies hold a great promise to provide additional care and support for patients with and survivors of cancer [1]. A growing number of digital interventions have been developed and designed for patients with cancer living with and beyond a cancer diagnosis [2-7].

Carla Vlooswijk, Sophia HE Sleeman, Jonas Pluis, Daphne Bakker, Lisanne de Groot, Eveliene Manten, Peter Heine, Olga Husson, Mies C van Eenbergen, Pieter Vandekerckhove

JMIR Form Res 2025;9:e60897

Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study

Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study

Following the launch of the dashboard, we conducted a cross-sectional study targeting adults older than 18 years who lived or worked in Cayuga County using a 20-question online Qualtrics survey [20]. We conducted 2 phases of participant recruitment, resulting in a convenience sample. During the initial recruitment phase, spanning from May to August 2023, participants were offered a US $10 Amazon gift card as an incentive.

Zhongxuan He, Monika Salvage, Corinna A Noel

Online J Public Health Inform 2025;17:e68977

A Resource-Efficient, High-Dose, Gamified Neurorehabilitation Program for Chronic Stroke at Home: Retrospective Real-World Analysis

A Resource-Efficient, High-Dose, Gamified Neurorehabilitation Program for Chronic Stroke at Home: Retrospective Real-World Analysis

All patients were assigned to a single-arm treatment group involving a high-dose, home-based training program (Figure 1 A–B). For the purposes of this work, we consider a high-dose program to be one that achieves a total dosage above 20 hours scheduled time, as these doses are generally considered to deliver outcomes above the minimum clinically important difference [2,5,29]. Overall, the program goal was to deliver 36 hours of training during the program.

Spencer A Arbuckle, Anna Sophie Knill, Michelle H Chan-Cortés, Gabriela Rozanski, Anastasia Elena Ford, Louis T Derungs, John W Krakauer, Naveed Ejaz, David Putrino, Jenna Tosto-Mancuso, Meret Branscheidt

JMIR Serious Games 2025;13:e69335

Language Models for Multilabel Document Classification of Surgical Concepts in Exploratory Laparotomy Operative Notes: Algorithm Development Study

Language Models for Multilabel Document Classification of Surgical Concepts in Exploratory Laparotomy Operative Notes: Algorithm Development Study

For this reason, we frame our problem in terms of a multilabel document classification task [6] where operative notes take on a series of binary labels as to whether or not a certain intraoperative finding (eg, bleeding and contamination) or technique (eg, bowel resection, hand-sewn anastomosis, and style of fascial closure) occurred during the case.

Jeremy A Balch, Sasank S Desaraju, Victoria J Nolan, Divya Vellanki, Timothy R Buchanan, Lindsey M Brinkley, Yordan Penev, Ahmet Bilgili, Aashay Patel, Corinne E Chatham, David M Vanderbilt, Rayon Uddin, Azra Bihorac, Philip Efron, Tyler J Loftus, Protiva Rahman, Benjamin Shickel

JMIR Med Inform 2025;13:e71176

Activity-Based Interventions to Increase Independence After Stroke In the Hospital Setting: Protocol for a Systematic Review

Activity-Based Interventions to Increase Independence After Stroke In the Hospital Setting: Protocol for a Systematic Review

Stroke is a leading cause of adult disability [1]; despite advances in acute treatments, the need for neurorehabilitation continues [2,3]. Stroke-related impairments can lead to difficulties in performing meaningful activities, such as showering or preparing a meal, and problems in participating more broadly in life, such as maintaining a home.

Tayla Grant, Laura Jolliffe, Kylie Wales, Emma Schneider, Avril E Drummond, Natasha A Lannin

JMIR Res Protoc 2025;14:e73133

Identifying Psychosocial, Self-Management, and Health Profiles Among Women With Chronic Pain Who Have Experienced Intimate Partner Violence and Those Who Have Not: Protocol for a 2-Phase Qualitative and Cross-Sectional Study Using AI Techniques

Identifying Psychosocial, Self-Management, and Health Profiles Among Women With Chronic Pain Who Have Experienced Intimate Partner Violence and Those Who Have Not: Protocol for a 2-Phase Qualitative and Cross-Sectional Study Using AI Techniques

Compared to women who have not experienced violence, those exposed to IPV against women report a higher prevalence of fibromyalgia, abdominal pain, genitourinary tract pain, pelvic and genital pain, headaches (including migraines), and back and neck pain [19-22]. A study conducted with 108 male and female patients with CP attending a rehabilitation center found that 56% had a current or past history of IPV, with more than 80% being women. Nearly 30% had experienced IPV within the previous year [23].

Ainara Nardi-Rodríguez, Sónia Bernardes, María Ángeles Pastor-Mira, Sofía López-Roig, Lidia Pamies-Aubalat, Andrés Sánchez-Prada, Victoria A Ferrer-Pérez, Ignacio Rodríguez-Rodríguez, Purificación Heras-González

JMIR Res Protoc 2025;14:e66396