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Digital Health Intervention to Reduce Malnutrition Among Individuals With Gastrointestinal Cancer Receiving Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy: Feasibility, Acceptability, and Usability Trial

Digital Health Intervention to Reduce Malnutrition Among Individuals With Gastrointestinal Cancer Receiving Cytoreductive Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy: Feasibility, Acceptability, and Usability Trial

Compared to baseline, average PG-SGA malnutrition scores saw a decrease of 6 points (P=.01), with a corresponding reduction in patients with high malnutrition risk (P=.03; Table 4). Functional Assessment of Cancer Therapy—General scores increased by an average of 20.5 points (P=.002), and Functional Assessment of Anorexia/Cachexia Treatment—Anorexia/Cachexia Scale scores increased by an average of 7.4 points (P=.03), indicating an improvement in participants’ health-related quality of life.

Yu Chen Lin, Ryan Hagen, Benjamin D Powers, Sean P Dineen, Jeanine Milano, Emma Hume, Olivia Sprow, Sophia Diaz-Carraway, Jennifer B Permuth, Jeremiah Deneve, Amir Alishahi Tabriz, Kea Turner

JMIR Cancer 2025;11:e67108

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

The LLM was significantly less accurate than both reviewer 1 (P Twelve medical questions and sample large language model (LLM) answers with the rates of concordance between the reviewers and the LLM. a R1: Reviewer 1. b R2: Reviewer 2. c TNM: Tumor-Node-Metastasis. We demonstrated and evaluated the extraction performance of a locally deployed, open-source LLM for a specific clinical NLP task.

Denise Lee, Akhil Vaid, Kartikeya M Menon, Robert Freeman, David S Matteson, Michael L Marin, Girish N Nadkarni

JMIR Form Res 2025;9:e64544

Urologists’ Estimation of Online Support Group Utilization Behavior of Their Patients With Newly Diagnosed Nonmetastatic Prostate Cancer in Germany: Predefined Secondary Analysis of a Randomized Controlled Trial

Urologists’ Estimation of Online Support Group Utilization Behavior of Their Patients With Newly Diagnosed Nonmetastatic Prostate Cancer in Germany: Predefined Secondary Analysis of a Randomized Controlled Trial

Thus, no patient in the COVID-19 group attended an F2 FG (7/308, 2.3% vs 0/379, 0%, respectively; P=.003). Most patients (471/687, 68.6%) reported having no interest in F2 FGs. Another 122 (17.8%) of the 687 patients did not know about F2 FGs, and 66 (9.6%) had other reasons for not attending. OSGs were used by 165 (24%) patients. The frequency of OSG use did not change significantly before (76/308, 24.7%) or during (89/379, 23.5%) the COVID-19 pandemic (P=.72).

Philipp Karschuck, Christer Groeben, Rainer Koch, Tanja Krones, Andreas Neisius, Sven von Ahn, Christian Peter Klopf, Steffen Weikert, Michael Siebels, Nicolas Haseke, Christian Weissflog, Martin Baunacke, Christian Thomas, Peter Liske, Georgi Tosev, Thomas Benusch, Martin Schostak, Joachim Stein, Philipp Spiegelhalder, Andreas Ihrig, Johannes Huber

J Med Internet Res 2025;27:e56092

Investigating Measurement Equivalence of Smartphone Sensor–Based Assessments: Remote, Digital, Bring-Your-Own-Device Study

Investigating Measurement Equivalence of Smartphone Sensor–Based Assessments: Remote, Digital, Bring-Your-Own-Device Study

The reported P value is defined as the proportion of permutations that resulted in a mean difference between the 2 permuted groups that is larger than the real observed mean difference between the subgroup and its reference group. Both unadjusted and adjusted P values (adjusted for multiple comparisons with false discovery rate correction using the Benjamini-Hochberg method) are reported.

Lito Kriara, Frank Dondelinger, Luca Capezzuto, Corrado Bernasconi, Florian Lipsmeier, Adriano Galati, Michael Lindemann

J Med Internet Res 2025;27:e63090

Innovating Care for Postmenopausal Women Using a Digital Approach for Pelvic Floor Dysfunctions: Prospective Longitudinal Cohort Study

Innovating Care for Postmenopausal Women Using a Digital Approach for Pelvic Floor Dysfunctions: Prospective Longitudinal Cohort Study

Statistical significance was defined as P Of the 3684 participants screened for eligibility, 633 participants were excluded (346 declined participation and 287 did not meet eligibility criteria; Figure 2). The program started with 3051 participants, of which 2367 participants completed it, translating into a completion rate of 77.6%. Study flowchart.

Ana P Pereira, Dora Janela, Anabela C Areias, Maria Molinos, Xin Tong, Virgílio Bento, Vijay Yanamadala, Jennesa Atherton, Fernando Dias Correia, Fabíola Costa

JMIR Mhealth Uhealth 2025;13:e68242