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Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care

Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care

Clinical effectiveness was quantified by calculating the change in anxiety symptoms, measured using the GAD-7, from baseline to final score, and estimating a within-participant effect size (Cohen d). A negative mean change denotes a reduction in GAD-7 total scores. Absolute Cohen d values are presented. The threshold for a clinically meaningful reduction in symptoms was defined as a change greater than the reliable change index of the GAD-7 scale (minimum of a 4-point reduction) [54].

Clare E Palmer, Emily Marshall, Edward Millgate, Graham Warren, Michael Ewbank, Elisa Cooper, Samantha Lawes, Alastair Smith, Chris Hutchins-Joss, Jessica Young, Malika Bouazzaoui, Morad Margoum, Sandra Healey, Louise Marshall, Shaun Mehew, Ronan Cummins, Valentin Tablan, Ana Catarino, Andrew E Welchman, Andrew D Blackwell

J Med Internet Res 2025;27:e69351