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Immunogenicity of COVID-19 Vaccination in Immunocompromised Patients (Auto-COVID-VACC): Protocol for Multicenter Prospective Noninterventional Study

Immunogenicity of COVID-19 Vaccination in Immunocompromised Patients (Auto-COVID-VACC): Protocol for Multicenter Prospective Noninterventional Study

Primary objective To analyze the available data on anti-spike–immunoglobulin G titers after repeated messenger RNA (m RNA) vaccinations in immunocompromised patients Secondary objectives To analyze the available data on neutralizing capacity against the Omicron-BA.1 variant after repeated m RNA vaccinations in immunocompromised patients To analyze the available data on neutralizing capacity against other Omicron sublineages after repeated m RNA vaccinations in immunocompromised patients To analyze the available

Louise Marie Cremer, Ullrich Bethe, Peter Borchmann, Veronica Di Cristanziano, Lutz Gieselmann, Sarah Grimm, Martin Hellmich, Julia Jakobs, Julia A Nacov, Julia M Neuhann, Juergen Prattes, Christoph Scheid, Rosanne Sprute, Gertrud Steger, Jannik Stemler, Sibylle C Mellinghoff, Oliver A Cornely

JMIR Res Protoc 2025;14:e60675