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Leveraging Cognitive and Speech Ecological Momentary Assessment in Individuals With Phenylketonuria: Development and Usability Study of Cognitive Fluctuations in a Rare Disease Population

Leveraging Cognitive and Speech Ecological Momentary Assessment in Individuals With Phenylketonuria: Development and Usability Study of Cognitive Fluctuations in a Rare Disease Population

Panel B shows performance on the semantic fluency task (n=20), where the y-axis represents participants’ ability to produce words within a specific category (eg, animals) during a set time frame. A higher score indicates better semantic fluency. Panel C shows performance on the MOT (n=20), with the y-axis reflecting participants’ accuracy. The MOT assesses speeded visual attention, and participants are asked to track a set of target circles.

Shifali Singh, Lisa Kluen, Katelin Curtis, Raquel Norel, Carla Agurto, Elizabeth Grinspoon, Zoe Hawks, Shawn Christ, Susan Waisbren, Guillermo Cecchi, Laura Germine

JMIR Form Res 2025;9:e63644