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Effectiveness of Smart Continence Care for People With Profound Intellectual and Multiple Disabilities: Cluster Randomized Trial

Effectiveness of Smart Continence Care for People With Profound Intellectual and Multiple Disabilities: Cluster Randomized Trial

Reference 12: Verblijfsduur van verpleeghuisbewoners met een Wlz indicatie Verpleging en Verzorging(https Nederlandse vertaling van de Mood, Interest en Pleasure Questionnaire(https://tinyurl.com/bdf2bsmw) Reference 24: Quality of Life-PMD: vragenlijst over de kwaliteit van leven van personen met ernstige beperkingen(https://research.rug.nl/en/publications/quality-of-life-pmd-vragenlijst-over-de-kwaliteit-van-leven-van-p Reference 39: Zonder context geen bewijs: over de illusie van evidence-based practice in de zorg(httpsRandomized trials (Editor: G. Eysenbach)*

Vivette JC van Cooten, Marieke FM Gielissen, Wouter den Hollander, Ghislaine APG van Mastrigt, Odile Smeets, Inge MB Bongers, Brigitte Boon

J Med Internet Res 2025;27:e66389

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

It was administered in doses ranging between 0.01 and 0.1 g/kg, 3 times daily either orally or intravenously (equivalent to 2.4-24 g/d for an 80 kg patient). Among patients with schizophrenia and catatonia, approximately 30 participants, the study showed a reduction of catatonic symptoms ranging from 60% to 70%. Specifically, there were improvements in anxiety, agitation, and restlessness.

Lilian Bot, Josine G van Mill, Laetitia J C A Smarius, Adriaan W Hoogendoorn, Bram W C Storosum, Christiaan H Vinkers, Gabriel E Jacobs, Gert Jan Lammers, Hanna M Heller, Jantine C A Colen-de Koning, Joris J B van der Vlugt, Marloes S Oudijn, Martijn S van Noorden, Pierre M Bet, Rolf Fronczek, Heleen S van der Heijden, Sjors M M Lange, Ysbrand D van der Werf, Eric R van Exel

JMIR Res Protoc 2025;14:e68356