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Linguistic Markers of Pain Communication on X (Formerly Twitter) in US States With High and Low Opioid Mortality: Machine Learning and Semantic Network Analysis

Linguistic Markers of Pain Communication on X (Formerly Twitter) in US States With High and Low Opioid Mortality: Machine Learning and Semantic Network Analysis

All machine learning procedures were conducted using the caret package in R (R Foundation for Statistical Computing) [30]. As the dataset was naturally imbalanced, with more tweets from high-mortality states, we used multiple strategies to mitigate potential classification bias. To enhance model learning, SMOTE was applied only to the training data, preventing overfitting while allowing the models to better distinguish between high- and low-mortality states based on linguistic features.

ShinYe Kim, Winson Fu Zun Yang, Zishan Jiwani, Emily Hamm, Shreya Singh

J Med Internet Res 2025;27:e67506

Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care

Combining Artificial Intelligence and Human Support in Mental Health: Digital Intervention With Comparable Effectiveness to Human-Delivered Care

Propensity matching was conducted using the Match IT package [52] in R (R Foundation) with the “nearest neighbor” methodology (average treatment effect in treated patients), matching for propensity score on a one-to-one ratio. Comparator groups showed high similarity with the digital program sample (see Table S2 in Multimedia Appendix 1).

Clare E Palmer, Emily Marshall, Edward Millgate, Graham Warren, Michael Ewbank, Elisa Cooper, Samantha Lawes, Alastair Smith, Chris Hutchins-Joss, Jessica Young, Malika Bouazzaoui, Morad Margoum, Sandra Healey, Louise Marshall, Shaun Mehew, Ronan Cummins, Valentin Tablan, Ana Catarino, Andrew E Welchman, Andrew D Blackwell

J Med Internet Res 2025;27:e69351