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Promoting Intergenerational Health in Rural Kentuckians With Diabetes (PIHRK’D): Protocol for a Longitudinal Cohort Study

Promoting Intergenerational Health in Rural Kentuckians With Diabetes (PIHRK’D): Protocol for a Longitudinal Cohort Study

This model assumes that a completely within-subject design with 5 testing occasions a first-order autocorrelation where r=0.5. Thus, with a total sample size of 60 participants, we would be powered to detect a small-to-medium effect.

Brittany L Smalls, Courtney L Ortz, Makenzie Barr-Porter, Heather Norman-Burgdolf, Christopher J McLouth, Brittany Harlow, Oluwatosin Leshi

JMIR Res Protoc 2025;14:e69301

Revisiting the Semantic Severity of Anxiety and Depression: Computational Linguistic Study of Normalization and Pathologization

Revisiting the Semantic Severity of Anxiety and Depression: Computational Linguistic Study of Normalization and Pathologization

First, we trained a Continuous Bag of Words word2vec model on the entire corpus using the word2vec package in R (R Foundation for Statistical Computing) [27]. Next, we created a mental health vector by averaging the vectors of words strongly associated with mental health (eg, therapy, psychiatry, and diagnosis; see Multimedia Appendix 1 for details). This vector was used as a reference point for identifying mental health–related language.

Vojtech Pisl, Ana-Maria Bucur, Ioana R Podina

J Med Internet Res 2025;27:e73950

Associations Between Daily Symptoms and Pain Flares in Rheumatoid Arthritis: Case-Crossover mHealth Study

Associations Between Daily Symptoms and Pain Flares in Rheumatoid Arthritis: Case-Crossover mHealth Study

All analyses were performed using R (version 4.3.1; R Foundation for Statistical Computing). Descriptive analysis was conducted to describe demographics, information about RA, and health status, as well as to characterize pain flares with 3 definitions. For each definition, pain flares were summarized by their frequency, duration, 30-day monthly rate, and the duration of impact. Conditional logistic regression was used to estimate the odds ratio (OR) for pain flare occurrence.

Ting-Chen Chloe Hsu, Belay B Yimer, Pauline Whelan, Christopher J Armitage, Katie Druce, John McBeth

JMIR Mhealth Uhealth 2025;13:e64889