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To assess the statistical significance of the observed accuracy, a permutation test with 10,000 permutations was conducted, where a low P value indicates a low probability that the observed accuracy could have been achieved by random chance.
The study protocol and experimental design were reviewed and approved by the IRB (IRB# 12689) at Indiana University.
JMIR Med Inform 2025;13:e68366
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A P value of
There are no published data on TRE in either healthy individuals or individuals with psoriasis on which to base calculations for the number of participants required to uncover distinct effects on IL-17 cytokine release.
JMIR Res Protoc 2025;14:e74999
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Although the mean of EARS and diary measurements correlated with the difference between EARS and diary measurements for bedtime and time-in-bed (P ≤.01), indicating a presence of proportional bias, there was no correlation present for risetime (P=.80). In addition, the average of EARS and Acti Graph measurements did not correlate with the difference between EARS and Acti Graph measurements for any of the sleep features (P ≥.20).
Bland-Altman plots.
JMIR Form Res 2025;9:e67455
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A 95% CI excluding zero will be interpreted to be statistically significant at a P
Additional data will be provided by the Client Satisfaction Questionnaire-8 and semistructured qualitative interviews with VACT-CP users (n=30) as well as by tracking website use information and calls or emails to research staff with concerns. Analysis of the postintervention interviews will be done using notes taken by one of the team members during the exit interview; interviews will also be audio recorded and transcribed.
JMIR Res Protoc 2025;14:e70601
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With 24 participants, a significant intervention effect (P
Primary outcome data will be analyzed using a multilevel model (R, version 4.0+; package lme4) to investigate whether there is a significant difference between the level of professional care support moments (frequency or duration) per week in the baseline phase and the effect phase. The dependent continuous variable is the frequency and duration of professional care support moments per week.
JMIR Res Protoc 2025;14:e67841
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However, a greater proportion of veterans with (compared to without) prevalent mental health conditions reported the following considerations to be “very important”: seeing information about DHTs on social media (those with mental health conditions: 42/428, 9.8%; those without mental health conditions: 19/328, 5.8%; χ22=6.2; P=.05); having community support through Veteran Service Organizations, churches, libraries, or other organizations to use DHTs (with: 56/427, 13.1%; without: 25/327, 7.6%; χ22=7.9; P=.02
JMIR Form Res 2025;9:e77113
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With 47.3% adult population with hypertension in the United States in 2021 [29], using 5% type 1 error (P=.05), the minimum sample size required to estimate participation in RBPM was 383 participants [30]. A minimum of 500 sample size has been recommended for detecting differences between the sample estimates and the population in observational studies involving logistic regression [31]. We stopped recruitment as soon as possible when we reached a sample size of 500.
J Med Internet Res 2025;27:e71926
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