JMIR Cancer

As the number of cancer survivors continues to grow, optimizing long-term survivorship care models has become increasingly important. Telehealth has the potential to improve access to health care for survivors; however, studies evaluating telehealth in this population remain limited. Additionally, concerns persist regarding equity in technology access and digital literacy.

With the rapid development of medical technology and the emphasis on early lung cancer screening, the detection rate of multiple primary lung cancer (MPLC) has increased in recent years. However, the prognostic determinants and clinical characteristics of patients with MPLC remain poorly characterized.

Effective communication about breast and cervical cancers remains a public health challenge, with widespread misinformation and barriers to cancer-related language understanding. Large language models (LLMs) offer potential for scalable health communication, yet trade-offs between quality, safety, and accessibility of general-purpose and medical-domain LLMs remain underexplored.

Digital health interventions are increasingly being integrated into oncological care to support patients in managing treatment-related symptoms and psychological distress. In a randomized controlled pilot trial, we investigated the feasibility and preliminary efficacy of a digital health app (SOFIA) among patients with cancer, including those in palliative care. SOFIA consists of an electronic patient-reported outcome (ePRO) assessment and coaching component. We showed good feasibility and high acceptability of SOFIA in routine clinical care.

Lung cancer remains the leading cause of cancer deaths in the United States; however, uptake of lung cancer screening (LCS) with low-dose computed tomography (LDCT) among eligible individuals remains low. Evidence suggests that limited knowledge, stigma, and false health beliefs contribute to the underuse of LDCT screening.

Focal high-intensity focused ultrasound (HIFU) is an emerging tissue-preserving treatment for localized prostate cancer (PCa) that aims to reduce functional impairment and psychological burden while maintaining oncological safety. Although its clinical use is increasing, prospective data on health-related quality of life (HRQoL) and psychological distress after focal hemiablation remain limited.

Older survivors of cancer face heightened risk of depression and anxiety related to cancer experiences, fear of recurrence, and aging-related difficulties. Conventional mental health monitoring approaches, such as clinical assessments and even electronic patient-reported outcomes, are limited by recall bias, patient burden, and infrequent data collection. Emerging patient-generated health data from wearables and smart home devices offer passive, low-burden, continuous monitoring, but their ability to capture mental health risks in older survivors of cancer remains unclear.

Breast cancer is the most common cancer among Canadian women, bringing complex demands for timely decision-making, coordination of multidisciplinary care, and efficient communication between patients and providers. The increasing reliance on fragmented and noninteroperable health information systems exacerbates workflow and documentation burdens, leading to inefficiencies and gaps in continuity of care. While nurse navigation programs partially bridge these gaps, most digital platforms remain poorly integrated into provider workflows, requiring manual tracking, which results in duplicated effort and reduced efficiency. Our team developed “MyJourney” at North York General Hospital (NYGH) in Ontario. It is a digital navigation platform that supports breast cancer care throughout the entire continuum, from diagnosis to survivorship.

Consumer smartwatches offer potential for continuous monitoring of physical activity during childhood cancer treatment. However, their validity for measuring step count and heart rate in this population has not been established.

Endocrine therapy is a fundamental treatment for hormone receptor–positive breast cancer. However, treatment-related symptoms may lead to poor adherence and premature discontinuation, adversely affecting clinical outcomes. eHealth technology interventions have been widely applied as potential tools to support patient education, symptom management, and adherence.

Despite the human papillomavirus (HPV) vaccine being available to males for the past 12 years, adolescent males continue to lag in HPV vaccine uptake due to a variety of factors. With the ubiquitous nature of social media use among this population, further research is needed to improve HPV vaccine confidence among young adolescent males using these platforms.

With increasing numbers of survivors with cancer, the importance of patient-centered information provision and communication to alleviate psychological burdens, such as anxiety and depression, is growing. However, substantial individual differences exist in patients with cancer information–seeking behaviors and use of support services, and few studies have comprehensively examined cognitive and psychological factors such as treatment status, sex, trust in information sources, and patient-provider relationships.