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A Machine Learning Approach to Differentiate Cold and Hot Syndrome in Viral Pneumonia Integrating Traditional Chinese Medicine and Modern Medicine: Machine Learning Model Development and Validation

A Machine Learning Approach to Differentiate Cold and Hot Syndrome in Viral Pneumonia Integrating Traditional Chinese Medicine and Modern Medicine: Machine Learning Model Development and Validation

For instance, Li et al’s [11] network analysis revealed that the leptin biomarker indicated low levels of energy metabolism in patients with cold syndrome, while the human monocyte chemoattractant protein-1 (CCL2/MCP1) biomarker suggested intensified immune regulation in patients with hot syndrome, based on a study involving patients with chronic superficial gastritis and chronic atrophic gastritis.

Xiaojie Jin, Yanru Wang, Jiarui Wang, Qian Gao, Yuhan Huang, Lingyu Shao, Jiali Zhao, Jintian Li, Ling Li, Zhiming Zhang, Shuyan Li, Yongqi Liu

JMIR Med Inform 2025;13:e64725