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Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

On the basis of an N of 180 and of .05, we would have 80% power to detect a Cohen f=0.25, a medium size effect [57]. Thus, after accounting for attenuation and 20% attrition [31,59,60], we will recruit 226 veterans (113 per condition). The sample will be stratified by site such that 113 veterans (with rounding) will be recruited separately from each VA site, with 57 veterans (with rounding) entering each condition at each site.

Kathryn Bruzios, Paige M Shaffer, Daniel M Blonigen, Michael A Cucciare, Michael Andre, Thomas Byrne, Jennifer Smith, David Smelson

JMIR Res Protoc 2025;14:e70750