TY - JOUR AU - Byrom, Bill AU - Everhart, Anthony AU - Cordero, Paul AU - Garratt, Chris AU - Meyer, Tim PY - 2025 DA - 2025/2/28 TI - Leveraging Patient-Reported Outcome Measures for Optimal Dose Selection in Early Phase Cancer Trials JO - JMIR Cancer SP - e64611 VL - 11 KW - clinical trials KW - early phase KW - dose finding KW - patient-reported outcome KW - PRO KW - electronic patient-reported outcome KW - ePRO KW - PRO-CTCAE KW - adverse events KW - tolerability KW - optimal dose KW - cancer trials KW - dose toxicity KW - oncology KW - drug development KW - electronic collection KW - dose level KW - pharmacodynamic KW - cytotoxic chemotherapy drugs KW - cytotoxic KW - chemotherapy drug KW - life-threatening disease KW - Common Terminology Criteria for Adverse Events SN - 2369-1999 UR - https://cancer.jmir.org/2025/1/e64611 UR - https://doi.org/10.2196/64611 DO - 10.2196/64611 ID - info:doi/10.2196/64611 ER -