TY  - JOUR
AU  - Andree, Rosa
AU  - Mujcic, Ajla
AU  - den Hollander, Wouter
AU  - van Laar, Margriet
AU  - Boon, Brigitte
AU  - Engels, Rutger
AU  - Blankers, Matthijs
PY  - 2024
DA  - 2024/6/20
TI  - Digital Smoking Cessation Intervention for Cancer Survivors: Analysis of Predictors and Moderators of Engagement and Outcome Alongside a Randomized Controlled Trial
JO  - JMIR Cancer
SP  - e46303
VL  - 10
KW  - smoking cessation
KW  - cancer survivors
KW  - engagement
KW  - digital intervention
KW  - eHealth
KW  - smoking
KW  - intervention
KW  - randomized controlled trial
KW  - predictor
KW  - RCT
KW  - smoker
KW  - addict
KW  - cessation
KW  - quit
KW  - cancer
KW  - oncology
AB  - Background: Recent studies have shown positive, though small, clinical effects of digital smoking cessation (SC) interventions for cancer survivors. However, research on associations among participant characteristics, intervention engagement, and outcomes is limited. Objective: This study aimed to explore the predictors and moderators of engagement and outcome of MyCourse-Quit Smoking (in Dutch: “MijnKoers-Stoppen met Roken”), a digital minimally guided intervention for cancer survivors. Methods: A secondary analysis of data from the randomized controlled trial was performed. The number of cigarettes smoked in the past 7 days at 6-month follow-up was the primary outcome measure. We analyzed interactions among participant characteristics (11 variables), intervention engagement (3 variables), and outcome using robust linear (mixed) modeling. Results: In total, 165 participants were included in this study. Female participants accessed the intervention less often than male participants (B=–11.12; P=.004). A higher Alcohol Use Disorders Identification Test score at baseline was associated with a significantly higher number of logins (B=1.10; P<.001) and diary registrations (B=1.29; P<.001). A higher Fagerström Test for Nicotine Dependence score at baseline in the intervention group was associated with a significantly larger reduction in tobacco use after 6 months (B=–9.86; P=.002). No other associations and no moderating effects were found. Conclusions: Overall, a limited number of associations was found between participant characteristics, engagement, and outcome, except for gender, problematic alcohol use, and nicotine dependence. Future studies are needed to shed light on how this knowledge can be used to improve the effects of digital SC programs for cancer survivors. Trial Registration: Netherlands Trial register NTR6011/NL5434; https://onderzoekmetmensen.nl/nl/trial/22832 
SN  - 2369-1999
UR  - https://cancer.jmir.org/2024/1/e46303
UR  - https://doi.org/10.2196/46303
DO  - 10.2196/46303
ID  - info:doi/10.2196/46303
ER  -