@Article{info:doi/10.2196/72522, author="Owens, Otis L and Leonard, Michael S", title="Evaluating an AI Chatbot ``Prostate Cancer Info'' for Providing Quality Prostate Cancer Screening Information: Cross-Sectional Study", journal="JMIR Cancer", year="2025", month="May", day="21", volume="11", pages="e72522", keywords="generative artificial intelligence; chatbot; chatGPT; prostate cancer; cancer screening; shared decision making; artificial intelligence", abstract="Background: Generative artificial intelligence (AI) chatbots may be useful tools for supporting shared prostate cancer (PrCA) screening decisions, but the information produced by these tools sometimes lack quality or credibility. ``Prostate Cancer Info'' is a custom GPT chatbot developed to provide plain-language PrCA information only from websites of key authorities on cancer and peer-reviewed literature. Objective: The objective of this paper was to evaluate the accuracy, completeness, and readability of Prostate Cancer Info's responses to frequently asked PrCA screening questions. Methods: A total of 23 frequently asked PrCA questions were individually input into Prostate Cancer Info. Responses were recorded in Microsoft Word and reviewed by 2 raters for their accuracy and completeness. Readability of content was determined by pasting responses into a web-based Flesch Kincaid Reading Ease Scores calculator. Results: Responses to all questions were accurate and culturally appropriate. In total, 17 of the 23 questions (74{\%}) had complete responses. The average readability of responses was 64.5 (SD 8.7; written at an 8th-grade level). Conclusions: Generative AI chatbots, such as Prostate Cancer Info, are great starting places for learning about PrCA screening and preparing men to engage in shared decision-making but should not be used as independent sources of PrCA information because key information may be omitted. Men are encouraged to use these tools to complement information received from a health care provider. ", issn="2369-1999", doi="10.2196/72522", url="https://cancer.jmir.org/2025/1/e72522", url="https://doi.org/10.2196/72522" }